KL
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Official Full Name
klotho
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Overview
This gene encodes a type-I membrane protein that is related to β-glucuronidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes ( -
Synonyms
KL; klotho;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- CHO
- E.coli
- HEK293
- Mammalian Cell
- Mammalian cells
- Fc
- His
- His (Fc)
- Avi
- His|GST
- His|T7
- N/A
- N
- SUMO
- Involved Pathway
- Protein Function
- Interacting Protein
- KL Related Articles
- KL Related Gene Family
KL involved in several pathways and played different roles in them. We selected most pathways KL participated on our site, such as Pentose and glucuronate interconversions, Starch and sucrose metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with KL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Pentose and glucuronate interconversions | AKR1B7;UGT2B15;UGT1AB;DHDH;UGT1A7C;ALDH2.1;UGT2A3;UGT2A2;CRYL1 |
Starch and sucrose metabolism | KL;TREH;UGP2A;UGDH;UGT5G1;PYGL;UGT1A6B;UGT1A7;AMY2A |
Metabolic pathways | DPYS;ALG9;DUT;PIGL;FAM213B;ACAA1A;ATP5L;EPT1;MTM1 |
Endocrine and other factor-regulated calcium reabsorption | GNAQ;VDR;KLK1B22;ESR1;PLCB2;GNAS;KLK1B24;BDKRB2;ATP1B2 |
KL has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KL itself. We selected most functions KL had, and list some proteins which have the same functions with KL. You can find most of the proteins on our site.
Function | Related Protein |
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protein binding | RXRA;MECOM;CCNB1IP1;FAM200A;TGFB1;MED9;ITGB3B;SDCCAG3;SPRY1 |
KL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KL here. Most of them are supplied by our site. Hope this information will be useful for your research of KL.
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- Q&As
- Reviews
Q&As (5)
Ask a questionKL protein may have a neuroprotective role and is being studied for its potential in preserving cognitive function and preventing neurodegenerative diseases.
Currently, there are no FDA-approved KL protein-based therapies, but research in this area is ongoing.
While research suggests a connection between KL protein and aging, it is not yet clear if KL protein supplementation can effectively slow down the aging process in humans.
KL protein levels can be measured in blood and urine samples using various laboratory techniques.
Yes, several clinical trials are investigating the potential therapeutic benefits of KL protein supplementation in kidney disease and other disorders.
Customer Reviews (3)
Write a reviewThe KL protein's reliability and ease of use have made it an essential component of my structural investigations.
Its ability to preserve structural integrity and facilitate high-resolution imaging has greatly enhanced my understanding of protein complexes and their interactions.
Furthermore, the KL protein has demonstrated great utility in protein electron microscopy structure analysis.
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