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LAIR2

  • Official Full Name

    leukocyte-associated immunoglobulin-like receptor 2

  • Overview

    The protein encoded by this gene is a member of the immunoglobulin superfamily. It was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily, including LAIR1. The function of this protein is unknown, although it is thought to be secreted and may help modulate mucosal tolerance. Two transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    LAIR2; leukocyte-associated immunoglobulin-like receptor 2; leukocyte associated Ig like receptor 2; CD306; CD306 antigen; LAIR 2; LAIR-2; LAIR2_HUMAN; Leukocyte associated immunoglobulin like receptor 2; MGC71634; OTTHUMP00000068389; OTTHUMP00000068390; leukocyte-associated Ig-like receptor 2; leukocyte-associated Ig-like receptor-2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Antibody
  • Protein Pre-coupled Magnetic Beads
  • Human
  • CHO cells
  • E.coli
  • HEK293
  • HEK293 cells
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian cells
  • Rabbit
  • Wheat Germ
  • C
  • His
  • Fc
  • Avi
  • His (Fc)
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LAIR2-743H Active Recombinant Human LAIR2, His-tagged Mammalian cells His
Human LAIR2-051H Active Recombinant Human LAIR2 protein, Fc/Avi-tagged, Biotinylated CHO cells Fc/Avi Gln22-Pro152
Human LAIR2-053H Active Recombinant Human LAIR2 protein, His/Avi-tagged, Biotinylated HEK293 cells His/Avi Glu23-Pro152
Human LAIR2-29000TH Recombinant Human LAIR2 Wheat Germ N/A 152 amino acids
Human LAIR2-5179H Recombinant Human LAIR2 protein HEK293 N/A Met 1-Pro 152
Human LAIR2-5586H Recombinant Human Leukocyte-associated Immunoglobulin-like Receptor 2, His-tagged E.coli His
Human LAIR2-6973H Recombinant Human LAIR2 protein(Met1-Pro152) HEK293 N/A Met1-Pro152
Human LAIR2-793H Recombinant Human LAIR2 protein(Met1-Pro152), His-tagged HEK293 C-His Met1-Pro152
Human LAIR2-209H Recombinant Human LAIR2 protein, His-tagged HEK293 His Gln22-Pro152
Human LAIR2-15841H Recombinant Human LAIR2, His-tagged E.coli His 22-135aa
Human LAIR2-1774HCL Recombinant Human LAIR2 cell lysate Human Cell N/A
Human LAIR2-342H Recombinant Human LAIR2 Protein, His-tagged HEK293 His 152
Human LAIR2-210H Active Recombinant Human LAIR2 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Gln22-Pro152
Human LAIR2-3326H Recombinant Human LAIR2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CAB11573RH Rabbit Anti-Human Leukocyte-associated immunoglobulin-like receptor 2 Monoclonal Antibody Rabbit N/A
Human LAIR2-3326H-B Recombinant Human LAIR2 Protein Pre-coupled Magnetic Beads HEK293
Human LAIR2-273HF Recombinant Full Length Human LAIR2 Protein In Vitro Cell Free System 152 amino acids
Human LAIR2-4405H Recombinant Human LAIR2 Protein (Met1-Pro152), C-His tagged Mammalian cells C-His Met1-Pro152
Human LAIR2-4406H Recombinant Human LAIR2 Protein (Gln22-Pro152), C-His tagged Mammalian cells C-His Gln22-Pro152
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • LAIR2 Related Articles
  • LAIR2 Related Research Area

LAIR2 involved in several pathways and played different roles in them. We selected most pathways LAIR2 participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with LAIR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemAP1G1;DCTN1;KIF18A;KLHL20;UBE2U;DNM1;CD200R1;SPSB4;CMTM2A
Immune SystemTRIM45;CD200R1;GM11711;IFIT11;HECTD3;TAX1BP1;NCR3LG1;TREML1;KIF4
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellCRTAM;LILRB1;CD300LB;LILRA2;KLRF1;KLRB1F;CD96;CD160;Siglece

LAIR2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LAIR2 itself. We selected most functions LAIR2 had, and list some proteins which have the same functions with LAIR2. You can find most of the proteins on our site.

Function Related Protein
protein bindingRPS14;JAGN1;S100A14;PYGM;FAM104A;OSTA;PLEKHA1;HSPBP1;SIAH1A

LAIR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LAIR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of LAIR2.

SGTA; EMILIN1

Xie, X; Wang, CY; et al. Development and evaluation of a sandwich ELISA method for the detection of human CD306. JOURNAL OF IMMUNOLOGICAL METHODS 396:65-73(2013).
Meyaard, L; de Vries, ARV; et al. The epithelial cellular adhesion molecule (Ep-CAM) is a ligand for the leukocyte-associated immunoglobulin-like receptor (LAIR) (Retracted Article. See vol 198, pg 1129, 2003). JOURNAL OF EXPERIMENTAL MEDICINE 194:107-112(2001).
Meyaard, L; Adema, GJ; et al. LAIR-1, a novel inhibitory receptor expressed on human mononuclear leukocytes. IMMUNITY 7:283-290(1997).
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