lars2
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  • Official Full Name
  • leucyl-tRNA synthetase 2, mitochondrial
  • Background
  • This gene encodes a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid.
  • Synonyms
  • LARS2; leucyl-tRNA synthetase 2, mitochondrial; probable leucyl-tRNA synthetase, mitochondrial; KIAA0028; leucine tRNA ligase 2; mitocondrial; LEURS; MGC26121; mitochondrial; LARS 2; Leucine translase; Leucine tRNA ligase 2 mitocondrial; Leucine tRNA ligase; Leucine--tRNA ligase; Leucyl tRNA synthetase 2; Leucyl tRNA synthetase 2 mitochondrial; Probable leucyl-tRNA synthetase; SYLM_HUMAN; OTTHUMP00000164232; OTTHUMP00000210279; OTTHUMP00000210280; leucine tRNA ligase 2, mitocondrial
Cat.#:LARS2-510HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human LARS2, GST-tagged
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Cat.#:LARS2-8961MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse LARS2 Protein
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Cat.#:LARS2-6037ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish LARS2
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Cat.#:LARS2-972HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human LARS2 cell lysate
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LARS2 Related Articles

Pierce, SB; Gersak, K; et al. Mutations in LARS2, Encoding Mitochondrial Leucyl-tRNA Synthetase, Lead to Premature Ovarian Failure and Hearing Loss in Perrault Syndrome. AMERICAN JOURNAL OF HUMAN GENETICS 92:614-620(2013).
Li, RH; Guan, MX; et al. Human Mitochondrial Leucyl-tRNA Synthetase Corrects Mitochondrial Dysfunctions Due to the tRNA(Leu(UUR)) A3243G Mutation, Associated with Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Symptoms and Diabetes. MOLECULAR AND CELLULAR BIOLOGY 30:2147-2154(2010).