LASS2
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Official Full Name
LAG1 homolog, ceramide synthase 2
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Overview
This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described. -
Synonyms
LAG1 homolog, ceramide synthase 2; LAG1 longevity assurance homolog 2 (S. cerevisiae); SP260; MGC987; CerS2; OTTHUMP00000033029; FLJ10243; OTTHUMP00000033030; L3; OTTHUMP00000033031; longevity assurance (LAG1, S. cerevisiae) homolog 2; ceramide synthase 2; Tumor metastasis-suppressor gene 1 protein; LAG1 longevity assurance 2; TMSG1; LAG1 longevity assurance homolog 2; LASS2; OTTHUMP00000033028;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rhesus Macaque
- E.coli
- HEK293
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | LASS2-512H | Recombinant Human LASS2, GST-tagged | E.coli | GST | C-66aa | |
| Mouse | LASS2-8965M | Recombinant Mouse LASS2 Protein | Mammalian Cell | His |
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| Mouse | LASS2-4999M | Recombinant Mouse LASS2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | LASS2-4999M-B | Recombinant Mouse LASS2 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rhesus Macaque | LASS2-2467R | Recombinant Rhesus monkey LASS2 Protein, His-tagged | Mammalian Cell | His |
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| Rhesus Macaque | LASS2-2288R | Recombinant Rhesus Macaque LASS2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rhesus Macaque | LASS2-2288R-B | Recombinant Rhesus Macaque LASS2 Protein Pre-coupled Magnetic Beads | HEK293 |
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- Involved Pathway
- Protein Function
- Interacting Protein
LASS2 involved in several pathways and played different roles in them. We selected most pathways LASS2 participated on our site, such as Sphingolipid metabolism, Metabolic pathways, Sphingolipid signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with LASS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Sphingolipid metabolism | SGPP2;DEGS1;SPTLC1;GLTP;SUMF2;SPHK2;PPAP2CB;UGCG;LASS2 |
| Metabolic pathways | REV3L;UGT1AB;DAO.2;TDO2;XYLT1;G6PCA.1;ATP6V0B;GLULC;AMPD1 |
| Sphingolipid signaling pathway | MAP2K2;PDPK1;DEGS2;PPP2R1B;SPTLC1;LASS1;CERS2;SPHK1;ACER1 |
LASS2 has several biochemical functions, for example, DNA binding, sphingosine N-acyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LASS2 itself. We selected most functions LASS2 had, and list some proteins which have the same functions with LASS2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | ZBTB42;ESR2A;VOX;TIGD1;SMAD3B;ZFP423;MYO18A;ZNF668;JUNBB |
| sphingosine N-acyltransferase activity | CERS3B;CERS2A;CERS5;CERS4A;CERS4;LASS2;LASS5;FAM57B;CERS2 |
LASS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LASS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of LASS2.
Ywhae; Hsd3b4; Hsd3b7
- Q&As
- Reviews
Customer Reviews (3)
Write a reviewBy using LASS2 protein, I can explore the mechanisms underlying cell division, cell cycle control, and the molecular pathways associated with these processes.
As a researcher utilizing LASS2 protein in my trials, I can highlight its advantages and the valuable support provided by the manufacturer in facilitating my research.
The protein's interaction with other APC/C subunits enables the study of its function and the investigation of its involvement in various cellular processes.
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