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LSM7

Official Full Name

LSM7 homolog, U6 small nuclear RNA associated
Overview

Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.
Synonyms

LSM7; LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae); U6 snRNA-associated Sm-like protein LSm7; YNL147W;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Zebrafish

Source

HEK293
HEK293T
Mammalian Cell

Tag

His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	LSM7-9170HCL	Recombinant Human LSM7 293 Cell Lysate	HEK293	N/A	Inquiry
Human	LSM7-5023H	Recombinant Human LSM7 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK	Inquiry
Mouse	LSM7-9336M	Recombinant Mouse LSM7 Protein	Mammalian Cell	His	Inquiry
Mouse	LSM7-5229M	Recombinant Mouse LSM7 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	LSM7-5229M-B	Recombinant Mouse LSM7 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	Lsm7-3859M	Recombinant Mouse Lsm7 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK	Inquiry
Zebrafish	LSM7-4443Z	Recombinant Zebrafish LSM7	Mammalian Cell	His	Inquiry
Chicken	LSM7-1481C	Recombinant Chicken LSM7	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
LSM7 Related Articles

LSM7 involved in several pathways and played different roles in them. We selected most pathways LSM7 participated on our site, such as RNA degradation, Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with LSM7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
RNA degradation	DCP2;PFKP;PABPC1L;CNOT10;CNOT1;PFKMB;CNOT6;RQCD1;DCP1A
Spliceosome	PRPF6;SR140;HNRNPM;ZMAT2;U2AF2;TCERG1;SRSF5;PPIE;SNRNP40

LSM7 has several biochemical functions, for example, contributes_to RNA binding, U6 snRNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LSM7 itself. We selected most functions LSM7 had, and list some proteins which have the same functions with LSM7. You can find most of the proteins on our site.

Function	Related Protein
contributes_to RNA binding	NUDT21;LSM7;CPSF6;SMX5
U6 snRNA binding	LSM8;LSM4;PRPF4;LSM7;EIF5A;DDX39B;RBM22;SART3;PRPF8
protein binding	CISD2;PMM2;CRKL;ZBTB43;PRDX1;CEP76;DGKZ;UBL7;DHPS

LSM7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LSM7 here. Most of them are supplied by our site. Hope this information will be useful for your research of LSM7.

LSM5; SNRPD3; LSM2; LSM4

Perez-Santangelo, S; Mancini, E; et al. Role for LSM genes in the regulation of circadian rhythms. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:15166-15171(2014).

Chowdhury, A; Kalurupalle, S; et al. Pat1 contributes to the RNA binding activity of the Lsm1-7-Pat1 complex. RNA-A PUBLICATION OF THE RNA SOCIETY 20:1465-1475(2014).