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LTBP1

Official Full Name

latent transforming growth factor beta binding protein 1
Overview

The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Synonyms

LTBP1; latent transforming growth factor beta binding protein 1; latent-transforming growth factor beta-binding protein 1; LTBP-1; TGF-beta1-BP-1; transforming growth factor beta-1-binding protein 1;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat

Source

E. coli
E.coli
HEK293
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	LTBP1-29149TH	Recombinant Human LTBP1	Wheat Germ	N/A	98 amino acids	Inquiry
Human	LTBP1-4591H	Recombinant Human LTBP1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	LTBP1-319H	Recombinant Human LTBP1 Protein, His-tagged	E. coli	His	600-739 aa	Inquiry
Human	LTBP1-317H	Recombinant Human LTBP1 Protein, His-tagged	E.coli	His	Asp1424~Glu1721	Inquiry
Human	LTBP1-320H	Recombinant Human LTBP1 Protein, GST-tagged	E. coli	GST	455-804 aa	Inquiry
Mouse	LTBP1-9347M	Recombinant Mouse LTBP1 Protein	Mammalian Cell	His		Inquiry
Mouse	Ltbp1-318M	Recombinant Mouse Ltbp1 Protein, His-tagged	E.coli	His	Asp1415~Glu1712	Inquiry
Mouse	LTBP1-5237M	Recombinant Mouse LTBP1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	LTBP1-5237M-B	Recombinant Mouse LTBP1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	LTBP1-3500R	Recombinant Rat LTBP1 Protein	Mammalian Cell	His		Inquiry
Rat	LTBP1-3156R	Recombinant Rat LTBP1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	LTBP1-3156R-B	Recombinant Rat LTBP1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Chicken	LTBP1-5465C	Recombinant Chicken LTBP1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
LTBP1 Related Research Area

LTBP1 involved in several pathways and played different roles in them. We selected most pathways LTBP1 participated on our site, such as TGF-beta signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with LTBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
TGF-beta signaling pathway	ACVR2B;RHOAA;E2F5;ACVR1;TGFBR1A;BMP7B;TGFBR1;BAMBIA;SMAD5

LTBP1 has several biochemical functions, for example, calcium ion binding, microfibril binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LTBP1 itself. We selected most functions LTBP1 had, and list some proteins which have the same functions with LTBP1. You can find most of the proteins on our site.

Function	Related Protein
calcium ion binding	CDH11;SMOC1;DLC;DNASE1L2;EHD4;ANXA6;PCDH2G29;LDLRB;CABP4
microfibril binding
protein binding	ATXN2;EIF2B5;ARGLU1;MTSS1;TMPRSS15;SMAD3;KRTAP4-12;PARP1;WRAP53
transforming growth factor beta binding	ACVR1;TGFBR2;VASN;HYAL2;ENG;THBS1;CD109;TGFBR1;LTBP4
transforming growth factor beta-activated receptor activity	ENG;BMPR2B;BMPR2A;TGFBR3;LTBP1;TGFBR2;TGFBR1;ACVRL1

LTBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LTBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LTBP1.

TGM2; PCOLCE; ATN1; TGFB1; FBN1

Other ECM Glycoproteins