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LTF

  • Official Full Name

    lactotransferrin

  • Overview

    This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
  • Synonyms

    LTF; lactotransferrin; LF; HLF2; GIG12; HEL110; talalactoferrin; neutrophil lactoferrin; growth-inhibiting protein 12; epididymis luminal protein 110;

  • Recombinant Proteins
  • Native Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bovine
  • Cattle
  • Dog
  • Goat
  • Human
  • Mouse
  • Pig
  • Rat
  • Bovine milk
  • Bovine Milk
  • E.coli
  • HEK293
  • HEK293T
  • Hman Plasma
  • Human Breast Milk
  • Human Cell
  • Human cells
  • Human Milk
  • Human Neutrophil
  • Human Whole Blood
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Rice Flour
  • Rice Grain
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • His|T7
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
  • MBP
  • C
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LTF-154H Recombinant Human LTF protein Rice Grain N/A
Human LTF-8196H Native Human Breast Milk Lactoferrin APO Human Breast Milk N/A
Human LTF-155H Recombinant Human LTF Rice Flour N/A
Human LTF-7666H Recombinant Human LTF protein, His-tagged E.coli His Glu542~Gln685 (Accession # P02788)
Human LTF-257H Recombinant Human LTF Mammalian Cell His
Human LTF-7667H Recombinant Human LTF protein, His-tagged E.coli His Leu337~Arg449 (Accession # P02788)
Human LTF-3873H Recombinant Human LTF, His tagged HEK293 His Met 1-Lys 710
Human LTF-1859HCL Recombinant Human LTF cell lysate Human Cell N/A
Human LTF-1062HFL Recombinant Full Length Human LTF Protein, C-Flag-tagged Mammalian cells Flag
Human LTF-4771H Native Human Lactotransferrin N/A
Human LTF-312H Native Human LTF protein Human Milk N/A
Human LTF-1057H Recombinant Human Lactoferrin Protein Human cells His
Human LTF-1327H Recombinant Human LTF Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human LTF-27590TH Native Human LTF Human Breast Milk N/A
Human LTF-175H Native Human lactoferrin Hman Plasma N/A Full length native Human lactoferrin
Human LTF-6210HF Recombinant Full Length Human LTF Protein, GST-tagged In Vitro Cell Free System GST 711 amino acids
Human LTF-1327H-B Recombinant Human LTF Protein Pre-coupled Magnetic Beads HEK293
Human LTF-4587H Recombinant Human LTF Protein, GST-tagged Wheat Germ GST
Human LTF-28999TH Native Human LTF Human Whole Blood N/A
Human LTF-1229H Recombinant Human LTF Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human LTF-4468H Recombinant Human LTF Protein (Met1-Lys710), N-His tagged E.coli N-His Met1-Lys710
Human LTF-5074H Recombinant Human LTF Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human LTF-8194H Native Human Neutrophil Lactoferrin Human Neutrophil N/A
Human LTF-2533H Recombinant Human LTF protein(20-710 aa), N-MBP & C-His-tagged HEK293 N-MBP & C-His 20-710 aa
Mouse Ltf-7668M Recombinant Mouse Ltf protein, His & GST-tagged E.coli His/GST Cys63~Gly193 (Accession # P08071)
Mouse Ltf-7669M Recombinant Mouse Ltf protein, His & GST-tagged E.coli His/GST Asp406~Arg549 (Accession # P08071)
Mouse LTF-907M Recombinant Mouse LTF Protein, His-tagged HEK293 His
Mouse Ltf-7670M Recombinant Mouse Ltf protein, His & GST-tagged E.coli His/GST Cys550~Gln707 (Accession # P08071)
Mouse LTF-1585MCL Recombinant Mouse LTF cell lysate Human Cell N/A
Mouse Ltf-3864M Recombinant Mouse Ltf Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat Ltf-7672R Recombinant Rat Ltf protein, His-tagged E.coli His Cys550~Lys668 (Accession # D3ZAB1)
Rat Ltf-7673R Recombinant Rat Ltf protein, His-tagged E.coli His Cys64~Gly193
Dog LTF-7664D Recombinant Dog LTF protein, His-tagged E.coli His Cys28~Lys351
Bovine LTF-3211B Native Bovine Lactoferrin Protein Bovine milk N/A
Bovine LTF-230B Native Bovine Apo-Lactoferrin Bovine Milk N/A
Bovine LTF-229B Native Bovine Lactoferrin Bovine Milk N/A
Cattle LTF-7663C Recombinant Cattle LTF protein, His & T7-tagged E.coli His/T7 Val25~Glu352 (Accession # P24627)
Goat LTF-7665G Recombinant Goat LTF protein, His-tagged E.coli His Val25~Glu352 (Accession # Q29477)
Pig LTF-7671P Recombinant Pig LTF protein, His & GST-tagged E.coli His/GST Val25~Glu348 (Accession # P14632)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • LTF Related Articles

LTF involved in several pathways and played different roles in them. We selected most pathways LTF participated on our site, such as Amyloid formation, Disease, Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with LTF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Amyloid formationODAM;RHBDL1;SEMG1;HIST2H3C;CST3;LTF;TGFBI;NAT8B;HIST4H4
DiseaseSUPT4H1;MIB1;ANTXR2;RLBP1;HEY2;RNF43;NMT2;PSTPIP2;CTBP2
Immune SystemSOCS3A;TNRC5;CFHL2;WIPF2;IFITM2;ARIH1L;ASB14;TRIM63;TRIM50
Infectious diseaseANTXR2;PPIAL4A;RCC1;TAF1L;STX1B;AP1S1;NMT2;CCDC167;EEF2
Latent infection of Homo sapiens with Mycobacterium tuberculosis
Metabolism of proteinsIGFBP5;EID3;FBXW5;DPAGT1;MIA3;GFER;WDR85;TIMM17A;MUCL1
Mtb iron assimilation by chelation
ROS production in response to bacteria

LTF has several biochemical functions, for example, DNA binding, heparin binding, iron ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LTF itself. We selected most functions LTF had, and list some proteins which have the same functions with LTF. You can find most of the proteins on our site.

Function Related Protein
DNA bindingIGHMBP2;MGAA;POLR2H;ZFP354A;WRNIP1;TRIM26;ZNF557;CERS5;KCNH7
heparin bindingELANE;APLP2;VEGFB;COL20A1;VTN;LTBP2;CCL2;ADAMTS8;NDNF
iron ion bindingHBQ1;CYP2C50;BA1;CYP2AA2;PTGIS;CYP3C1L2;CYP4A10;CYP2AD3;LEPREL2
protein bindingFOXR2;PSMD4;CNST;FBXO11;GATC;IL6R;NR3C1;BTK;FEM1B
protein serine/threonine kinase activator activitySTK3;CALM3;IGF2;CAB39;LTF;MAP2K1;CDK5R1;SPRY2;CALM1
serine-type endopeptidase activityKLK1B22;PRTN3;PRSS37;CLPP;F2;PIK3IP1;ELA2L;PRSS59.1;PRSS44

LTF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LTF here. Most of them are supplied by our site. Hope this information will be useful for your research of LTF.

p27958-pro_0000037570; CALM; p27958-pro_0000037569; NCL; p27958-pro_0000037573; SGK1; Dynll1; CDK5RAP3; Ikbip

Reder, AT; Oger, JF; et al. Short-term and long-term safety and tolerability of interferon beta-1b in multiple sclerosis. MULTIPLE SCLEROSIS AND RELATED DISORDERS 3:294-302(2014).
Fallahi, P; Katz, R; et al. Aspirin insensitive thrombophilia: Transcript profiling of blood identifies platelet abnormalities and HLA restriction. GENE 520:131-138(2013).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
How is LTF applied in the management of gastrointestinal disorders? 07/16/2022

LTF can be used to manage conditions like inflammatory bowel disease (IBD) due to its anti-inflammatory properties.

Can LTF be used to promote wound healing? 12/25/2018

Yes, LTF's antimicrobial and anti-inflammatory properties make it useful in wound healing applications.

How does LTF benefit patients with celiac disease? 01/01/2018

LTF may help celiac patients by promoting gut health and reducing inflammation caused by gluten consumption.

Can LTF be used to prevent or treat infections? 07/11/2017

Yes, LTF's ability to bind to bacteria and viruses can help prevent and treat infections.

Are there any side effects associated with LTF supplementation for anemia? 03/06/2016

LTF is generally well-tolerated, but in some cases, it may cause minor gastrointestinal discomfort.

Customer Reviews (3)

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Reviews
01/16/2018

    In addition to providing impeccable protein quality, the manufacturer offers excellent technical support that can effectively address any challenges I may encounter during my research.

    01/06/2017

      Whether it involves experimental design, protocol optimization, or data analysis, their expertise can help me navigate through complexities, saving valuable time and resources.

      03/31/2016

        Their knowledgeable and responsive team of experts is readily available to provide guidance, troubleshooting assistance, and answer any inquiries or concerns I may have.

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