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LYAR

  • Official Full Name

    Ly1 antibody reactive clone

  • Overview

    LYAR, also known as Ly1 antibody reactive clone, has been found to regulate the intracellular strength that is stimulated by both T and B cell antigen receptors. It is essential for immune tolerance and certain changes to its function could stimulate the development of autoreactivity. LYAR is important in the immunological synapse and functions to inhibit the T cell response. LYAR is highly expressed in indifferentiated embryonic stem cells and may be important in maintaining the stem cell identity.
  • Synonyms

    LYAR; Ly1 reactive clone; cell growth-regulating nucleolar protein; protein expressed in male leptotene and zygotene spermatocytes 264; MLZ-264;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • Yeast
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LYAR-1040HCL Recombinant Human LYAR cell lysate N/A
Human LYAR-4563H Recombinant Human LYAR Protein, GST-tagged Wheat Germ GST
Human LYAR-1578H Recombinant Human LYAR protein, His & T7-tagged E.coli His/T7 Lys288~Lys379 (Accession # Q9NX58)
Human LYAR-1854H Recombinant Human LYAR Protein (1-379 aa), His-tagged Yeast His 1-379 aa
Human LYAR-6232HF Recombinant Full Length Human LYAR Protein, GST-tagged In Vitro Cell Free System GST 379 amino acids
Human LYAR-4977H Recombinant Human LYAR Protein (Lys288-Lys379), N-His tagged E.coli N-His Lys288-Lys379
Mouse LYAR-9382M Recombinant Mouse LYAR Protein Mammalian Cell His
Mouse LYAR-5260M-B Recombinant Mouse LYAR Protein Pre-coupled Magnetic Beads HEK293
Mouse Lyar-1579M Recombinant Mouse Lyar protein, His & T7-tagged E.coli His/T7 Gly270~Lys388 (Accession # Q08288)
Mouse LYAR-5260M Recombinant Mouse LYAR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat LYAR-3512R Recombinant Rat LYAR Protein Mammalian Cell His
Rat LYAR-3168R Recombinant Rat LYAR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat LYAR-3168R-B Recombinant Rat LYAR Protein Pre-coupled Magnetic Beads HEK293
Rat Lyar-1580R Recombinant Rat Lyar protein, His & T7-tagged E.coli His/T7 Lys271~Lys386 (Accession # Q6AYK5)
Rhesus Macaque LYAR-2601R Recombinant Rhesus monkey LYAR Protein, His-tagged Mammalian Cell His
Rhesus Macaque LYAR-2421R Recombinant Rhesus Macaque LYAR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque LYAR-2421R-B Recombinant Rhesus Macaque LYAR Protein Pre-coupled Magnetic Beads HEK293
Zebrafish LYAR-10948Z Recombinant Zebrafish LYAR Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • LYAR Related Articles

LYAR involved in several pathways and played different roles in them. We selected most pathways LYAR participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LYAR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

LYAR has several biochemical functions, for example, metal ion binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LYAR itself. We selected most functions LYAR had, and list some proteins which have the same functions with LYAR. You can find most of the proteins on our site.

Function Related Protein
metal ion bindingZFP346;ZIC2A;IMPDH1;SDHDA;RIOK1;ZNF438;ZFP41;FCN1;ZNF781
poly(A) RNA bindingSREK1;RPSA;FAM98C;SNRNP40;SNRPB;ARF1;EIF3I;RBM26;ZNF638
protein bindingISYNA1;DNAJA3;DOCK10;SMAGP;DDL-2;LIN28B;LRRK2;THOP1;FLVCR1

LYAR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LYAR here. Most of them are supplied by our site. Hope this information will be useful for your research of LYAR.

PRKRA; BEND7; SDCBP2; 20475405; KPNA6; DKC1; KRT36

Miyazawa, N; Yoshikawa, H; et al. Human cell growth regulator Ly-1 antibody reactive homologue accelerates processing of preribosomal RNA. GENES TO CELLS 19:273-286(2014).
Ju, JY; Wang, Y; et al. Human fetal globin gene expression is regulated by LYAR. NUCLEIC ACIDS RESEARCH 42:9740-9752(2014).
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