LYN
-
Official Full Name
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
-
Overview
Lyn, one of the Src family members, is predominantly expressed in hematopoietic cells. Two tyrosine residues have been reported to play a crucial role in the regulation of protein tyrosine kinases of the Src family. Autophosphorylation of Tyr396 (equivale -
Synonyms
LYN; v-yes-1 Yamaguchi sarcoma viral related oncogene homolog; tyrosine-protein kinase Lyn; JTK8; lck/Yes-related novel protein tyrosine kinase; p53Lyn; p56Lyn; FLJ26625;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Insect (sf21)
- Insect cell
- Insect Cell
- Mammalian Cell
- Sf21
- Sf9 Insect Cell
- Wheat Germ
- DDK
- Flag
- GST
- GST|His
- His
- His (Fc)
- Avi
- Myc
- Myc|DDK
- N/A
- N
- FLAG
- No tag
- Involved Pathway
- Protein Function
- Interacting Protein
- LYN Related Articles
- LYN Related Research Area
LYN involved in several pathways and played different roles in them. We selected most pathways LYN participated on our site, such as Chemokine signaling pathway, NF-kappa B signaling pathway, Platelet activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with LYN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Chemokine signaling pathway | PRKCZ;CDC42;CXCR3;GSK3A;XCL2;CCL22;GM1987;PRKACG;PF4V1 |
NF-kappa B signaling pathway | NFKB1;LTBR;TRAF1;TNFRSF13C;BIRC3;TICAM2;MAP3K7;CCL4;CCL21B |
Platelet activation | MAPK13;MYL12B;BTK;VAMP8;F2R;GP9;ITPR3;ROCK2;MAPK11 |
B cell receptor signaling pathway | GSK3AB;LCP2A;ARPC5;AKT2;PIK3CB;NFKBIE;PIK3R1;AKT1;PILRB |
Fc epsilon RI signaling pathway | SOS1;PRKCA;MAPK1;GM-CSF;PLA2G4F;IL5;MAPK9;PIK3CG;MAP2K7 |
Fc gamma R-mediated phagocytosis | ASAP3;ASAP2;MAPK3;GSN;AMPH;FCGR2A;SYK;PRKCA;RAC1 |
Long-term depression | CRHR1;PPP2CA;GNAI1;PPP2R1B;MAPK1;GNA11;NOS1;GNAZ;GRIA3 |
Epithelial cell signaling in Helicobacter pylori infection | ATP6V0C;ATP6V1C2;IKBKB;ATP6V0B;MAPK10;MAP2K4;MAPK9;CXCR1;ATP6V1E2 |
Epstein-Barr virus infection | IKBKB;TAB1;HLA-B;IRAK1;MAP2K7;MAP2K3;TBPL2;GTF2E2;EIF2AK4 |
Viral carcinogenesis | LYN;PMAIP1;HIST2H2BE;MAPK3;HIST1H4N;HIST1H2BD;HIST1H2BJ;TRAF5;PIK3R5 |
LYN has several biochemical functions, for example, ATP binding, SH3 domain binding, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LYN itself. We selected most functions LYN had, and list some proteins which have the same functions with LYN. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
ATP binding | UBE2KB;PAK2A;VRK2;GUCY2F;CHD4;PMVK;KIF5AA;RET;MYO18A |
SH3 domain binding | ERRFI1;CD2AP;VASPA;FMN1;ARHGAP6;CTTNBP2;ABL1;HCLS1;CYBA |
enzyme binding | RARA;UGT1A6B;PUS7;DAXX;TNKS2;UGT1A9;SELS;N4BP2L2;PLCB1 |
gamma-tubulin binding | NDN;LYN;TUBGCP2;RAD51L3;NME2;CEP57;CEP57L1;DIXDC1;BRCA2 |
glycosphingolipid binding | Il2;LYN;SELP;LAMC1;LAMB1;SELL;Cel;LAMA1 |
integrin binding | FN1A;THY1;CTGFB;EDIL3;ITGA6;PXN;WISP1A;WISP3;FBLN1 |
ion channel binding | KCNJ11;S100A10;KCNQ3;PACS1A;LRRK2;CALM;YWHAQ;CAV1;KCNE4 |
non-membrane spanning protein tyrosine kinase activity | TNK2;PTK2BB;PTK2B;ITK;TYK2;FYNA;PRKCD;EIF2AK2;JAK1 |
phosphoprotein binding | MID1;PLAT;SRC;SNCA;DPYS;DPYSL3;IGF2R;MTOR;MID2 |
platelet-derived growth factor receptor binding | PDGFC;LYN;PTEN;PDGFAA;ITGB3;IL1R1;FIGF;PDGFD;PDGFRB |
protein binding | MAB21L1;CCT5;ACTR1B;SH2D2A;GBF1;OOEP;HIPK2;ZNF131;CTDNEP1 |
protein tyrosine kinase activity | NTRK2B;EPHA4A;IGF1R;SRMS;WEE1;KDR;PDGFRB;FYN;EPHA7 |
receptor binding | IDUA;SLC9A3R2;TNFSF10;ACOT2;CCL2;BMP3;TNFSF18;NPPA;DAO |
receptor signaling protein tyrosine kinase activity | ERBB2;ERBB4A;EGFRA;INSR;TYRO3;KITA;KITB;EGFR;KIT |
ubiquitin protein ligase binding | CUL1;CDKN1A;UBE2B;BCL10;SLC22A18;TMEM189;UBXN1;TPI1;MC1R |
LYN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LYN here. Most of them are supplied by our site. Hope this information will be useful for your research of LYN.
EGFR; polg_hcvh; polg_hcvco; KHDRBS1; polg_hcvj4; PTK2; tip_shv2c
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All LYN Products
Required fields are marked with *
My Review for All LYN Products
Required fields are marked with *