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Lipc

  • Official Full Name

    lipase, hepatic

  • Overview

    LIPC encodes hepatic triglyceride lipase, which is expressed in liver. LIPC has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake.
  • Synonyms

    LIPC; lipase, hepatic; HL; HTGL; LIPH; HDLCQ12;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bacillus subtilis
  • Human
  • Mouse
  • Pig
  • Rat
  • E. coli or Yeast
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • His
  • His (Fc)
  • Avi
  • His|GST
  • SUMO
  • Myc
  • DDK
  • MYC
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LIPC-267H Recombinant Human LIPC, His-tagged E.coli His
Human LIPC-268H Recombinant Human LIPC, His-tagged E.coli His
Human LIPC-4726HCL Recombinant Human LIPC 293 Cell Lysate HEK293 N/A
Human LIPC-269H Recombinant Human LIPC Protein, Myc/DDK-tagged HEK293T Myc/DDK
Human LIPC-3238H Recombinant Human LIPC Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human LIPC-1298H-B Recombinant Human LIPC Protein Pre-coupled Magnetic Beads HEK293
Human LIPC-1298H Recombinant Human LIPC Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human LIPC-258HFL Recombinant Full Length Human LIPC Protein, C-Flag-tagged Mammalian cells Flag
Human LIPC-3725H Recombinant Human LIPC Protein (Glu47-Pro478), N-His tagged E.coli N-His Glu47-Pro478
Human LIPC-3724H Recombinant Human LIPC Protein (Glu347-Pro478), His tagged E.coli His Glu347-Pro478
Mouse LIPC-9127M Recombinant Mouse LIPC Protein Mammalian Cell His
Mouse Lipc-7644M Recombinant Mouse Lipc protein, His & GST-tagged E.coli His/GST Ser159~Ile415 (Accession # P27656)
Mouse Lipc-391M Recombinant Mouse Lipase, Hepatic, His-tagged E.coli His
Mouse LIPC-5097M Recombinant Mouse LIPC Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse LIPC-3292M Recombinant Mouse LIPC protein, His-SUMO-tagged E.coli His-SUMO Ser159~Ile415
Mouse LIPC-5097M-B Recombinant Mouse LIPC Protein Pre-coupled Magnetic Beads HEK293
Mouse LIPC-3293M Recombinant Mouse LIPC protein, His-tagged E.coli His Ser159~Ile415
Mouse Lipc-1165M Recombinant Mouse Lipc Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat Lipc-7646R Recombinant Rat Lipc protein, His & GST-tagged E.coli His/GST Ile191~Thr466 (Accession # P07867)
Bacillus subtilis LIPC-0554B Recombinant Bacillus subtilis LIPC protein, His-tagged E. coli or Yeast His
Pig LIPC-7645P Recombinant Pig LIPC protein, His & GST-tagged E.coli His/GST Gln103~Tyr356 (Accession # B8XSI5)
  • Involved Pathway
  • Protein Function
  • Interacting Protein

Lipc involved in several pathways and played different roles in them. We selected most pathways Lipc participated on our site, such as Glycerolipid metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with Lipc were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycerolipid metabolismPNPLA3;AGPAT3;PNLIP;AKR1B1;ALDH1B1;DGAT1;AKR1B8;DGAT2;GLA
Metabolic pathwaysDCXR;Atp5g2;PAFAH1B2;SC4MOL;CYP27A1;TUSC3;GUSB;COX4I2;GLCE

Lipc has several biochemical functions, for example, apolipoprotein binding, heparin binding, low-density lipoprotein particle binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Lipc itself. We selected most functions Lipc had, and list some proteins which have the same functions with Lipc. You can find most of the proteins on our site.

Function Related Protein
apolipoprotein bindingPCSK9;LPL;PLG;LIPC;ABCA1;LRP1;SCARB1;LRP4;CANX
heparin bindingZNF207;LPL;WISP1A;CCL8;CCDC80;LXN;FN1;LIPC;FMOD
low-density lipoprotein particle bindingCOLEC12;SORL1;SCARF1;LIPC;THBS1;ANKRA2;SCARB1;LDLR;CRP
phospholipase activityPNLIPRP2;CEL.1;LIPC;DAGLB;PLA2G4AA;PLA2G10;LIPK;ABHD2B;LIPI
triglyceride lipase activityCel;AADAC;PNPLA2;LIPCA;CEL.1;PNLIPRP3;LIPC;CES1D;LIPF

Lipc has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Lipc here. Most of them are supplied by our site. Hope this information will be useful for your research of Lipc.

ADHFE1

  • Q&As
  • Reviews

Q&As (5)

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How does genetic variation in the LIPC gene impact individual susceptibility to metabolic disorders? 07/10/2021

Genetic variations in the LIPC gene can influence enzyme activity, impacting lipid metabolism. Certain variants are associated with an increased risk of metabolic disorders such as dyslipidemia and insulin resistance.

How does LIPC contribute to lipid homeostasis, and what implications does this have for cardiovascular health? 04/02/2020

LIPC contributes to lipid homeostasis by breaking down lipids, regulating their levels in the bloodstream. Dysregulation of LIPC activity is associated with imbalances in lipid profiles and an increased risk of cardiovascular diseases.

How is the LIPC gene regulated, and what factors influence its expression? 08/15/2019

The expression of the LIPC gene is influenced by various factors, including dietary fat intake, hormonal signals, and genetic predisposition. Transcriptional regulators and epigenetic modifications also play a role.

How does LIPC interact with other proteins involved in lipid metabolism, and what are the consequences of disruptions in these interactions? 03/21/2019

LIPC interacts with various proteins in lipid metabolism pathways. Disruptions in these interactions can lead to impaired lipid processing, contributing to metabolic disorders and cardiovascular diseases.

What techniques are commonly used in the lab to study LIPC expression and activity? 12/28/2018

Techniques such as RT-PCR, Western blotting, and enzyme assays are commonly used to study LIPC expression and activity. Additionally, advanced methods like mass spectrometry provide insights into post-translational modifications.

Customer Reviews (3)

Write a review
Reviews
03/02/2022

    Product works wonders!

    11/05/2020

      Very satisfied with the product!

      07/18/2019

        Exceptional service!

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