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NCS1

  • Official Full Name

    neuronal calcium sensor 1

  • Overview

    This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene.<br/>Mouse monoclonal antibody raised against a full-length recombinant FREQ.
  • Synonyms

    FLUP; FREQ; DKFZp761L1223; neuronal calcium sensor 1; frequenin homolog; OTTHUMP00000022356; frequenin-like protein; frequenin-like ubiquitous protein; NCS1; neuronal calcium sensor 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NCS1-29296TH Recombinant Human NCS1, His-tagged E.coli His 190 amino acids
Human NCS1-637H Recombinant Human NCS1 Mammalian Cell His
Human NCS1-29298TH Recombinant Human NCS1, His-tagged E.coli His
Human NCS1-2353H Recombinant Human Neuronal Calcium Sensor 1, His-tagged E.coli His
Human NCS1-3939HCL Recombinant Human NCS1 293 Cell Lysate HEK293 N/A
Human NCS1-4492H Recombinant Human NCS1 Protein, GST-tagged Wheat Germ GST
Human NCS1-2929H Recombinant Human NCS1 protein, GST-tagged E.coli GST 1-190aa
Human NCS1-3595H Recombinant Human NCS1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human NCS1-5145HF Recombinant Full Length Human NCS1 Protein, GST-tagged In Vitro Cell Free System GST 190 amino acids
Human NCS1-3595H-B Recombinant Human NCS1 Protein Pre-coupled Magnetic Beads HEK293
Mouse NCS1-10491M Recombinant Mouse NCS1 Protein Mammalian Cell His
Mouse Ncs1-4318M Recombinant Mouse Ncs1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse NCS1-5948M-B Recombinant Mouse NCS1 Protein Pre-coupled Magnetic Beads HEK293
Mouse NCS1-5948M Recombinant Mouse NCS1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken NCS1-6929C Recombinant Chicken NCS1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NCS1 Related Articles

NCS1 involved in several pathways and played different roles in them. We selected most pathways NCS1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NCS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

NCS1 has several biochemical functions, for example, calcium ion binding, magnesium ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NCS1 itself. We selected most functions NCS1 had, and list some proteins which have the same functions with NCS1. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingHPCA;EFCAB6;MYL1;SCUBE1;NCS1A;ITSN2;CAPNS1A;CD69;CALM3
magnesium ion bindingNUDT18;DUT;SNRK;ILVBL;FARS2;PPM1BB;NCS1;PRPS2;COMT
protein bindingACTN4;ESD;PPP2R3C;UBASH3A;ZNF543;TBCB;ZC3H18;CST3;NKX2
protein kinase bindingCALM;PDPK1;ATF2;AGTR1A;SHC3;FAM83E;TRPV4;TNIP2;SPRED2
voltage-gated calcium channel activityNALCN;CACNB4B;CACNA1BA;TPC3;CACNB2B;CALHM1;CACNB1;CATSPER3;CACNA1C

NCS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NCS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NCS1.

DTX2; NBL1; DTX2

Simmons, KJ; Jackson, SM; et al. Molecular mechanism of ligand recognition by membrane transport protein, Mhp1. EMBO JOURNAL 33:1831-1844(2014).
Guedan, S; Chen, X; et al. ICOS-based chimeric antigen receptors program bipolar T(H)17/T(H)1 cells. BLOOD 124:1070-1080(2014).
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