PDPN
-
Official Full Name
Podoplanin
-
Overview
This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified. -
Synonyms
T1A; GP36; GP40; Gp38; OTS8; T1A-2; AGGRUS; HT1A-1; PA2.26; PDPN; podoplanin; T1-alpha; hT1alpha-1; hT1alpha-2; PA2.26 antigen; glycoprotein 36; OTTHUMP00000009639; OTTHUMP00000009640; OTTHUMP00000221492; OTTHUMP00000221493; OTTHUMP00000221495; OTTHUMP00000221496; OTTHUMP00000221498; OTTHUMP00000221499; glycoprotein, 36-KD; lung type I cell membrane associated glycoprotein; lung type-I cell membrane-associated glycoprotein (T1A-2);
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Canis lupus familiaris (Dog) (Canis familiaris)
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- E.coli
- E.coli expression system
- HEK293
- Human Cell
- Insect Cell
- Insect Cells
- Mammalian Cell
- Mammalian cells
- C
- hFc
- His
- Fc
- Avi
- FC
- GST
- His (Fc)
- His|GST
- N/A
- N
- Tag
- Free
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | PDPN-2320H | Active Recombinant Human PDPN, Fc-His tagged | HEK293 | FC/His | Met1-Lys123 | |
Human | PDPN-571H | Active Recombinant Human PDPN Protein, Fc Chimera | Mammalian cells | Fc | ||
Human | PDPN-2321H | Active Recombinant Human PDPN protein, His-tagged | HEK293 | His | Met1-Lys123 | |
Human | PDPN-31033TH | Recombinant Human PDPN, His-tagged | E.coli | His | ||
Human | PDPN-28603TH | Recombinant Human PDPN, His-tagged | E.coli | His | 109 amino acids | |
Human | PDPN-379H | Recombinant Human Podoplanin, His-tagged | E.coli | His | ||
Human | PDPN-956H | Recombinant Human Podoplanin (Fragment) | E.coli | N/A | ||
Human | PDPN-2517HCL | Recombinant Human PDPN cell lysate | Human Cell | N/A | ||
Human | PDPN-42H | Recombinant Human PDPN Protein, Fc/Avi-tagged | HEK293 | Fc/Avi | ||
Human | PDPN-1895H | Active Recombinant Human PDPN protein, His-tagged | HEK293 | His | Ala 23 - Leu 131 | |
Human | PDPN-301248H | Recombinant Human PDPN protein, GST-tagged | E.coli | GST | Ala99-Leu207 | |
Human | PDPN-133H-B | Recombinant Human PDPN Protein Pre-coupled Magnetic Beads | HEK293 | |||
Human | PDPN-133H | Recombinant Human PDPN Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Human | PDPN-1897H | Active Recombinant Human PDPN protein, Fc-tagged | HEK293 | Fc | Ala 23 - Leu 131 | |
Human | PDPN-2706H | Active Recombinant Human PDPN protein, hFc&His-tagged | HEK293 | hFc&His | Glu97–Lys199 | |
Human | PDPN-3915H | Recombinant Human PDPN Protein (Ala23-Leu131), C-His tagged | Mammalian cells | C-His | Ala23-Leu131 | |
Human | PDPN-3917H | Recombinant Human PDPN Protein (Ala23-Pro238), His tagged | E.coli | His | Ala23-Pro238 | |
Human | PDPN-3918H | Recombinant Human PDPN Protein (Ala23-Gly146), N-His tagged | E.coli | N-His | Ala23-Gly146 | |
Mouse | Pdpn-8027M | Recombinant Mouse Pdpn protein, His & GST-tagged | E.coli | His/GST | Gly23~Val138 (Accession # Q62011) | |
Mouse | PDPN-855M | Active Recombinant Mouse PDPN protein, His-tagged | Insect Cells | His | Met1-Lys133 | |
Mouse | Pdpn-832M | Active Recombinant Mouse Pdpn protein, His&hFc-tagged | HEK293 | His&hFc | Met1-Leu141 | |
Mouse | PDPN-2687MCL | Recombinant Mouse PDPN cell lysate | Human Cell | N/A | ||
Mouse | PDPN-470MCL | Recombinant Mouse PDPN cell lysate | Insect Cell | N/A | ||
Mouse | Pdpn-7215M | Recombinant Mouse Pdpn Protein | E.coli | |||
Rat | PDPN-4358R | Recombinant Rat PDPN Protein | Mammalian Cell | His | ||
Rat | Pdpn-1149R | Active Recombinant Rat Pdpn protein(Met1-Leu135), hFc-tagged | HEK293 | C-hFc | Met1-Leu135 | |
Rat | PDPN-4018R | Recombinant Rat PDPN Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | PDPN-4018R-B | Recombinant Rat PDPN Protein Pre-coupled Magnetic Beads | HEK293 | |||
Canis lupus familiaris (Dog) (Canis familiaris) | RFL36442CF | Recombinant Full Length Dog Podoplanin(Pdpn) Protein, Tag-Free | E.coli expression system | Tag-Free | Full Length of Mature Protein (23-169) | |
Homo sapiens (Human) | RFL7986HF | Recombinant Full Length Human Podoplanin(Pdpn) Protein, Tag-Free | E.coli expression system | Tag-Free | Full Length of Mature Protein (23-162) | |
Mus musculus (Mouse) | RFL9698MF | Recombinant Full Length Mouse Podoplanin(Pdpn) Protein, Tag-Free | E.coli expression system | Tag-Free | Full Length of Mature Protein (23-172 ) | |
Rattus norvegicus (Rat) | RFL25405RF | Recombinant Full Length Rat Podoplanin(Pdpn) Protein, Tag-Free | E.coli expression system | Tag-Free | Full Length of Mature Protein (23-166) |
- Involved Pathway
- Protein Function
- Interacting Protein
- PDPN Related Articles
- PDPN Related Research Area
PDPN involved in several pathways and played different roles in them. We selected most pathways PDPN participated on our site, such as GPVI-mediated activation cascade, Hemostasis, Platelet activation, signaling and aggregation, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDPN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
GPVI-mediated activation cascade | C6orf25;RHOGA;PIK3R6;PDPN;CLEC1B;RHOB;FCER1GL;G6b;LCP2A |
Hemostasis | DGKG;HBBE1.1;PHF21A;PRTN3;KIFC1;RHOB;F9B;KIF15;HBG2 |
Platelet activation, signaling and aggregation | SERPINF2B;MMRN1;FCER1GL;ABHD12;CD9B;PLEK;MMRN2A;STXBP3;IGF2B |
PDPN has several biochemical functions, for example, NOT amino acid transmembrane transporter activity, NOT folic acid transporter activity, NOT water channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PDPN itself. We selected most functions PDPN had, and list some proteins which have the same functions with PDPN. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
NOT amino acid transmembrane transporter activity | |
NOT folic acid transporter activity | |
NOT water channel activity | PDPN;MIPB |
NOT water transmembrane transporter activity |
PDPN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDPN here. Most of them are supplied by our site. Hope this information will be useful for your research of PDPN.
TOM1L1
- Q&As
- Reviews
Q&As (7)
Ask a questionPDPN facilitates cancer progression by promoting tumor cell migration and enhancing metastatic potential.
PDPN is crucial for lymphatic vessel development and maintenance, aiding in lymphatic system function.
Changes in PDPN expression contribute to fibrosis and lymphedema pathogenesis, affecting tissue structure and fluid balance.
PDPN is significant in forming and stabilizing blood-lymphatic vessel junctions, ensuring proper vascular function.
PDPN affects platelet aggregation and blood coagulation, playing a role in thrombosis and hemostasis.
PDPN expression on tumor cells alters their interaction with the immune system, impacting immune evasion.
PDPN plays a role in wound healing and tissue regeneration, influencing cell migration and tissue repair.
Customer Reviews (3)
Write a reviewSwift protein expression optimization support; greatly appreciated.
Accurate protein structural characterization; indispensable for our research.
Reliable mass spectrometry analysis; pivotal for proteomics experiments.
Ask a Question for All PDPN Products
Required fields are marked with *
My Review for All PDPN Products
Required fields are marked with *