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PEX10

Official Full Name

peroxisomal biogenesis factor 10
Overview

This gene encodes a protein involved in import of peroxisomal matrix proteins. This protein localizes to the peroxisomal membrane. Mutations in this gene result in phenotypes within the Zellweger spectrum of peroxisomal biogenesis disorders, ranging from neonatal adrenoleukodystrophy to Zellweger syndrome. Alternative splicing results in two transcript variants encoding different isoforms.
Synonyms

PEX10; peroxisomal biogenesis factor 10; peroxisome biogenesis factor 10; RNF69; RING finger protein 69; Gm142; MGC1998; OTTHUMP00000001658; AV128229; NALD; peroxin 10; peroxisome assembly protein 10; RP23-298E4.1; peroxin-10; OTTHUMP00000221357; OTTHUMP00000221358;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Cynomolgus Monkey
Dictyostelium discoideum (Slime mold)
Human
Mouse
Zebrafish

Source

E.coli
E.coli expression system
HEK293
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PEX10-3296HCL	Recombinant Human PEX10 293 Cell Lysate	HEK293	N/A		Inquiry
Human	PEX10-301481H	Recombinant Human PEX10 protein, GST-tagged	E.coli	GST	Leu111-Leu160	Inquiry
Mouse	PEX10-12642M	Recombinant Mouse PEX10 Protein	Mammalian Cell	His		Inquiry
Mouse	PEX10-6642M	Recombinant Mouse PEX10 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	PEX10-6642M-B	Recombinant Mouse PEX10 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Cynomolgus Monkey	PEX10-779C	Recombinant Cynomolgus PEX10 Protein, His-tagged	Mammalian Cell	His		Inquiry
Cynomolgus Monkey	PEX10-523C	Recombinant Cynomolgus Monkey PEX10 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Cynomolgus Monkey	PEX10-523C-B	Recombinant Cynomolgus Monkey PEX10 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Dictyostelium discoideum (Slime mold)	RFL16549DF	Recombinant Full Length Dictyostelium Discoideum Peroxisome Biogenesis Factor 10(Pex10) Protein, His-Tagged	E.coli expression system	His	Full Length (1-374)	Inquiry
Zebrafish	PEX10-1518Z	Recombinant Zebrafish PEX10	Mammalian Cell	His		Inquiry
Chicken	PEX10-4202C	Recombinant Chicken PEX10	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

PEX10 involved in several pathways and played different roles in them. We selected most pathways PEX10 participated on our site, such as Peroxisome, which may be useful for your reference. Also, other proteins which involved in the same pathway with PEX10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Peroxisome	ABCD3;PEX2;GSTK1;ACSL3B;PEX1;PEX10;PHYH;ACSL1;EPHX2

PEX10 has several biochemical functions, for example, protein C-terminus binding, protein binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PEX10 itself. We selected most functions PEX10 had, and list some proteins which have the same functions with PEX10. You can find most of the proteins on our site.

Function	Related Protein
protein C-terminus binding	IFT52;VPS4B;NPAT;PIAS3;YAP1;XRCC6;MED12;HSPG2;SDCBP
protein binding	ESYT2;C3;CD209;RAB11A;PIKFYVE;EXOC1;SYTL2;EDNRB;FUT11
zinc ion binding	ENPP1;ZMYM5;RNF26;JADE3;BFAR;Adamts19;USP20;UMPS;GATA1A

PEX10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PEX10 here. Most of them are supplied by our site. Hope this information will be useful for your research of PEX10.

PEX19; UBE2I; MKRN3; CGRRF1; PCGF6; PEX14; PEX5