PLCB2
-
Official Full Name
phospholipase C, beta 2
-
Synonyms
PLCB2;phospholipase C, beta 2;1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2;FLJ38135;PLC-beta-2;phospholipase C-beta-2;phosphoinositide phospholipase C-beta-2;1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- E.coli
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
- His|T7
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | PLCB2-8262H | Recombinant Human PLCB2 protein, His & T7-tagged | E.coli | His/T7 | Met1~Arg250 (Accession # Q00722) |
|
| Human | PLCB2-483HCL | Recombinant Human PLCB2 lysate | HEK293 | N/A |
|
|
| Human | PLCB2-3687H | Recombinant Human PLCB2 protein, His-tagged | E.coli | His | 1 - 100 aa | |
| Mouse | Plcb2-8263M | Recombinant Mouse Plcb2 protein, His & T7-tagged | E.coli | His/T7 | Met1~Arg250 (Accession # A3KGF7) |
|
| Mouse | PLCB2-12918M | Recombinant Mouse PLCB2 Protein | Mammalian Cell | His |
|
|
| Mouse | PLCB2-6814M | Recombinant Mouse PLCB2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
|
|
| Mouse | PLCB2-6814M-B | Recombinant Mouse PLCB2 Protein Pre-coupled Magnetic Beads | HEK293 |
|
||
| Rat | Plcb2-8264R | Recombinant Rat Plcb2 protein, His & T7-tagged | E.coli | His/T7 | Met1~Arg250 (Accession # O89040) |
|
| Rat | PLCB2-4500R | Recombinant Rat PLCB2 Protein | Mammalian Cell | His |
|
|
| Rat | PLCB2-4160R | Recombinant Rat PLCB2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
|
|
| Rat | PLCB2-4160R-B | Recombinant Rat PLCB2 Protein Pre-coupled Magnetic Beads | HEK293 |
|
||
| Rhesus Macaque | PLCB2-3462R | Recombinant Rhesus monkey PLCB2 Protein, His-tagged | Mammalian Cell | His |
|
|
| Rhesus Macaque | PLCB2-3280R-B | Recombinant Rhesus Macaque PLCB2 Protein Pre-coupled Magnetic Beads | HEK293 |
|
||
| Rhesus Macaque | PLCB2-3280R | Recombinant Rhesus Macaque PLCB2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
|
- Involved Pathway
- Protein Function
- Interacting Protein
- PLCB2 Related Articles
- PLCB2 Related Signal Pathway
PLCB2 involved in several pathways and played different roles in them. We selected most pathways PLCB2 participated on our site, such as Inositol phosphate metabolism, Metabolic pathways, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLCB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Inositol phosphate metabolism | PLD4;INPP5L;PLCG1;NUDT3;PIP5K1B;PIK3CB;OCRL;PIP5K1BB;MTMR1A |
| Metabolic pathways | ALDH1A2;PYCR1A;SYNJ1;POLR1D;CMPK;ACSBG1;LPIN2;EXT2;ALPL |
| Rap signaling pathway | KIT;RHOA;INS;PLCE1;PFN3;FLT1;FGF22;KLK1B4;FGF4 |
| Calcium signaling pathway | TACR1A;PTGER3;PLCG1;P2RX5;TMEM8C;AGTR1A;PHKG1B;PLCB3;PPP3CC |
| cGMP-PKG signaling pathway | PPP1R12A;PLCB3;TRPC6;ATP1A3;PDE2A;ATP2A1;PRKG2;GUCY1A3;PIK3R3 |
| Chemokine signaling pathway | CCL25;GNB2;PIK3R1;PLCB4;PIK3R2;FGR;CCL17;STAT5B;IL-8 |
| Phosphatidylinositol signaling system | PLCD4;DGKE;INPP5A;PIP5K1A;CALM3;MTMR3;MTMR14;PIP4K2B;PIK3CD |
| Sphingolipid signaling pathway | MAPK3;TRP53;PPP2R5D;ASAH2;PPP2R1B;GNAI3;SMPD2;BAX;TRAF2 |
| Phospholipase D signaling pathway | GRB2;GAB1;PLCB2;PLA2G4A;GNAS;PIK3R5;RAF1;LPAR5;TSC1 |
| Adrenergic signaling in cardiomyocytes | AKT2;PPP2R2C;CALM2B;KCNE1;ATP1B1A;CALM2A;SCN1BA;PIK3R5;ADCY1 |
| Vascular smooth muscle contraction | CALML3;PRKACA;CALML5;PRKACBA;GNAQ;PLCB4;ARHGEF1;CACNA1DA;CYP4A12A |
| Wnt signaling pathway | NFATC4;PRKACB;ROCK2;MAPK10;LRP6;TBL1XR1;CSNK2A2A;CAMK2G;BAMBI |
| Gap junction | TUBA1C;PDGFAA;PRKCBA;PRKG2;TUBB;TUBB6;GRB2;PDGFC;PRKCB |
| Platelet activation | AKT2;PLA2G4F;PPP1CA;GNAI1;COL27A1;FGA;PRKCI;PIK3CG;RAP1A |
| Circadian entrainment | GNG5;GRIN2D;MAPK3;GNG8;PLCB2;PRKCG;GRIA3;GUCY1B3;MAPK1 |
| Long-term potentiation | GRIN2D;RAP1A;KRAS;PRKCG;GRM5;PRKACA;GNAQ;GRIA1;GRM1 |
| Retrograde endocannabinoid signaling | FAAH;SLC17A8;PRKACB;NAPEPLD;GRIA3;MAPK13;GNAI1;DAGLB;GNB1 |
| Glutamatergic synapse | GNG12;DLGAP1;SHANK1;SLC1A1;GNAQ;GRIN2A;PPP3CB;PPP3CC;TRPC1 |
| Cholinergic synapse | GNG8;GNG10;KCNQ4;CREB5;KRAS;PIK3CD;GNB1;KCNJ6;MAP2K1 |
| Serotonergic synapse | HTR1E;CYP2J5;MAPK3;PLA2G4C;GNG3;CYP2C70;HTR2B;GNG8;PLCB3 |
| Dopaminergic synapse | GNG12;GNG11;PRKCG;KCNJ6;GNG3;PPP2R2D;DRD1;KIF5C;CREB3L4 |
| Long-term depression | GNAS;CRHR1;GNA12;PLCB1;PRKG2;MAP2K1;PLCB2;GNAO1;ARAF |
| Taste transduction | TAS2R136;GNB1;GNAT3;TAS2R125;GNAS;TAS1R3;KCNB1;TAS2R38;TAS2R108 |
| Inflammatory mediator regulation of TRP channels | PRKCG;ASIC4;ITPR3;PLCB2;IGF1;CYP2C70;KLK1B4;CALML3;CAMK2D |
| Insulin secretion | PRKCG;CREB3L1;KCNMB1;GIP;ATF4;STX1A;PLCB1;CCKAR;PDX1 |
| GnRH signaling pathway | ADCY1A;SOS1;MAPK10;GNA11;CALM2;PRKCA;CALM1;PRKCBB;MAP2K7 |
| Estrogen signaling pathway | PRKACG;KCNJ6;CREB5;HSP90B1;AKT2;ATF6B;MAP2K1;PIK3R3;CALM1 |
| Melanogenesis | WNT2B;GNAS;Adcy4;KITLGB;PRKCBB;DVL3A;PRKACG;WNT8A;WNT16 |
| Thyroid hormone synthesis | Adcy4;ATP1A3;ATP1B2;PLCB2;PLCB4;ATP1B1;PRKCB;ATP1A1;LRP2 |
| Thyroid hormone signaling pathway | EP300;HIF1A;MED27;PLN;PIK3CG;PRKCG;MTOR;HDAC2;PRKACB |
| Oxytocin signaling pathway | CACNA2D3;GUCY1A3;PRKCA;PLCB3;MAP2K5;PRKACB;RYR2;PIK3CD;CAMK4 |
| Renin secretion | REN2;GUCY1A3;CLCA4;PLCB4;CLCA5;CALM2;PLCB1;GNAQ;NPR1 |
| Aldosterone synthesis and secretion | AGTR1;SLC14A2;ATF1;STAR;PLCB1;AKR1C1;NR4A2;HSD3B2;ADCY7 |
| Endocrine and other factor-regulated calcium reabsorption | PLCB1;VDR;ATP1B4;ATP1A1;PRKACG;PRKCA;DNM3;KLK2;KLK1 |
| Salivary secretion | CALML3;ATP1B1;ATP2B4;GNAS;STATH;ATP1A1;PRKG1;CST4;HTN1 |
| Gastric acid secretion | CALM3;MYLK;KCNJ15;HRH2;SLC26A7;SLC9A4;KCNE2;MYLK3;SST |
| Pancreatic secretion | KCNQ1;PLA2G1B;RAB27B;Cel;SLC26A3;CELA2A;Adcy4;PLA2G5;CELA2B |
| Carbohydrate digestion and absorption | PIK3R1;SI;HK2;AMY1B;ATP1A4;G6PC;PIK3CA;ATP1A1;SLC2A5 |
| Alzheimers disease | CAPN2;SNCA;CALM4;ATP5A1;COX6B1;CALML5;NDUFA13;mt-Atp8;COX7B2 |
| Huntingtons disease | PLCB2;COX7A1;BDNF;NDUFS1;CASP8;IFT57;NDUFS8;UQCR10;NDUFA13 |
| Chagas disease (American trypanosomiasis) | GNAL;LOC100033925;GNAQ;GNA15;GNAO1;PIK3CA;TGFB1;IL-8;PLCB3 |
| African trypanosomiasis | IL6;PRKCG;PLCB3;LAMA4;IL1B2;TLR9;ICAM1;PLCB2;APOA1 |
| Amoebiasis | HSPB1;IL12A;LAMC2;PIK3CG;ACTN3;COL2A1;PRKCG;CXCL8;SERPINB6 |
| Pathways in cancer | FGFR1;LAMA3;PLCB4;WNT16;KITLG;MAPK10;Flt3l;TCEB1;MSH2 |
PLCB2 has several biochemical functions, for example, calcium ion binding, phosphatidylinositol phospholipase C activity, phospholipase C activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PLCB2 itself. We selected most functions PLCB2 had, and list some proteins which have the same functions with PLCB2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | FLG;REPS1;PCDH1G3;ANXA4;EFHD2;DOC2D;MYL12A;PLA2G2D;KCNIP3 |
| phosphatidylinositol phospholipase C activity | PLCE1;PLCD3;CHRM3;PLCD3A;PLCD1A;PLCL1;CCL5;PLCB2;PLCB3 |
| phospholipase C activity | PDIA3;PLCG2;PLCB4;PLCB3;PLCG1;PLCL1;ADORA1;PLCE1;PLCH2 |
| signal transducer activity | MAPKAPK2B;PLCB1;TAS2R120;IRS4;CCR1L1;GMFB;RGS6;SLC44A2;TRAF3 |
PLCB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLCB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLCB2.
npm_alk
Chae, JJ; Park, YH; et al. Connecting Two Pathways Through Ca2+ Signaling: NLRP3 Inflammasome Activation Induced by a Hypermorphic PLCG2 Mutation. ARTHRITIS & RHEUMATOLOGY 67:563-567(2015).
Maranhao, RC; Leite, ACA; et al. Development of Anti-Atherosclerosis Therapy Based on the Inflammatory and Proliferative Aspects of the Disease. CURRENT PHARMACEUTICAL DESIGN 21:1196-1204(2015).
- Q&As
- Reviews
Ask a Question for All PLCB2 Products
Required fields are marked with *
My Review for All PLCB2 Products
Required fields are marked with *
