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PLEK

  • Official Full Name

    pleckstrin

  • Overview

    Pleckstrin is a protein found in platelets. The name derives from platelet and leukocyte C kinase substrate and the KSTR string of amino acids.
  • Synonyms

    PLEK; pleckstrin; P47; platelet 47 kDa protein; FLJ27168;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PLEK-1773H Recombinant Human PLEK, His-tagged E.coli His 1-350aa
Human PLEK-28515TH Recombinant Human PLEK Wheat Germ N/A 110 amino acids
Human PLEK-30882TH Recombinant Human PLEK Wheat Germ N/A 350 amino acids
Human PLEK-497H Recombinant Human PLEK, His tagged E.coli His
Human PLEK-3119HCL Recombinant Human PLEK 293 Cell Lysate HEK293 N/A
Human PLEK-373HF Recombinant Full Length Human PLEK Protein In Vitro Cell Free System 350 amino acids
Mouse Plek-4923M Recombinant Mouse Plek Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat PLEK-4512R Recombinant Rat PLEK Protein Mammalian Cell His
Rat PLEK-4172R-B Recombinant Rat PLEK Protein Pre-coupled Magnetic Beads HEK293
Rat PLEK-4172R Recombinant Rat PLEK Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish PLEK-11094Z Recombinant Zebrafish PLEK Mammalian Cell His
Chicken PLEK-6426C Recombinant Chicken PLEK Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PLEK Related Articles

PLEK involved in several pathways and played different roles in them. We selected most pathways PLEK participated on our site, such as Hemostasis, Platelet activation, signaling and aggregation, Platelet degranulation, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLEK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
HemostasisSLC7A8A;SERPINB8;TFA;ANGPT2A;TRPC7;KIF18A;CD9B;CBX5;BA2
Platelet activation, signaling and aggregationFCER1GL;GNA13B;CAP1;SCG3;GAS6;SERPINF2B;CLU;F13A1B;CLEC1B
Platelet degranulationCLU;AASS;SCG3;CAP1;GAS6;SERPINF2B;SPARC;IGF2B;PLEK
Response to elevated platelet cytosolic Ca2+F13A1B;SRGN;WDR1;CD9B;IGF2B;SPARC;CALU;STXBP3;PLEK

PLEK has several biochemical functions, for example, phosphatidylinositol-3,4-bisphosphate binding, protein binding, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PLEK itself. We selected most functions PLEK had, and list some proteins which have the same functions with PLEK. You can find most of the proteins on our site.

Function Related Protein
phosphatidylinositol-3,4-bisphosphate bindingNCF1;PHLDA3;TTPA;RAG2;MAPKAP1;AKT1;DAPP1;KIF16B;FAM21C
protein bindingRXRB;RIPK1;CD200R1;MYCBP;GMCL1;ZFYVE1;HSPB1;ACVR2A;SPSB1
protein homodimerization activityTBX15;HSF2;MAFA;RPL7;UGT1A6A;MAP3K10;TFRC;DNTTIP1;CD200
protein kinase C bindingDACT3;MARCKS;PEA15A;FEZ1;PARD6A;TRPV4;NELL2;TIRAP;SQSTM1

PLEK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLEK here. Most of them are supplied by our site. Hope this information will be useful for your research of PLEK.

INPP5A; SDPR; PF4; THBS1; ACTN1; MSN

Honarpisheh, H; Glusac, EJ; et al. Cytokeratin 20 expression in basaloid follicular hamartoma and infundibulocystic basal cell carcinoma. JOURNAL OF CUTANEOUS PATHOLOGY 41:916-921(2014).
Jeon, SY; Kim, DC; et al. Expression Patterns of Gli-1, Pleckstrin Homology-Like Domain, Family A, Member 1, Transforming Growth Factor- beta 1/beta 2, and p63 in Sebaceous and Follicular Tumors. ANNALS OF DERMATOLOGY 26:713-721(2014).
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