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POLR2F

  • Official Full Name

    polymerase (RNA) II (DNA directed) polypeptide F

  • Overview

    This gene encodes the sixth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes, that is also shared by the other two DNA-directed RNA polymerases. In yeast, this polymerase subunit, in combination with at least two other subunits, forms a structure that stabilizes the transcribing polymerase on the DNA template.
  • Synonyms

    POLR2F; polymerase (RNA) II (DNA directed) polypeptide F; DNA-directed RNA polymerases I, II, and III subunit RPABC2; DNA directed RNA polymerase II 14.4 kda polypeptide; HRBP14.4; RPB6; DNA directed RNA polymerase II polypeptide F; DNA directed RNA polymerases I, II, and III 14.4 kDa polypeptide; hsRPB6; POLRF; RPABC14.4; RPABC2; RPB14.4; RPC15; RPB6 homolog; OTTHUMP00000199278; OTTHUMP00000199281; RNA Polymerase II subunit 14.4 kD; DNA-directed RNA polymerase II subunit F; RNA polymerases I, II, and III subunit ABC2; DNA direct;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • C
  • Myc
  • DDK
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human POLR2F-154H Recombinant Human POLR2F, His-tagged E.coli His 1-127aa
Human POLR2F-30687TH Recombinant Human POLR2F E.coli N/A
Human POLR2F-1844H Recombinant Human POLR2F, GST-tagged E.coli GST 1-127aa
Human POLR2F-3033HCL Recombinant Human POLR2F 293 Cell Lysate HEK293 N/A
Human POLR2F-374H Recombinant Human POLR2F Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Mouse POLR2F-13096M Recombinant Mouse POLR2F Protein Mammalian Cell His
Mouse Polr2f-4998M Recombinant Mouse Polr2f Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse POLR2F-6923M-B Recombinant Mouse POLR2F Protein Pre-coupled Magnetic Beads HEK293
Mouse POLR2F-6923M Recombinant Mouse POLR2F Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat POLR2F-4570R Recombinant Rat POLR2F Protein Mammalian Cell His
Rat POLR2F-4230R-B Recombinant Rat POLR2F Protein Pre-coupled Magnetic Beads HEK293
Rat POLR2F-4230R Recombinant Rat POLR2F Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque POLR2F-3516R Recombinant Rhesus monkey POLR2F Protein, His-tagged Mammalian Cell His
Rhesus Macaque POLR2F-3334R Recombinant Rhesus Macaque POLR2F Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque POLR2F-3334R-B Recombinant Rhesus Macaque POLR2F Protein Pre-coupled Magnetic Beads HEK293
Zebrafish POLR2F-666Z Recombinant Zebrafish POLR2F Mammalian Cell His
Chicken POLR2F-6299C Recombinant Chicken POLR2F Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

POLR2F involved in several pathways and played different roles in them. We selected most pathways POLR2F participated on our site, such as Purine metabolism, Pyrimidine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with POLR2F were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Purine metabolismPRPS1B;ADSSL;POLE2;POLR2L;NPR1;PRPS2;PPAT;PDE5AB;ENTPD1
Pyrimidine metabolismNME2B.2;AK9;POLR2J3;NME2B.1;CMPK2;DCTPP1;UPP1;POLR2F;NT5C1B-RDH14
Metabolic pathwaysGALNTL4;NOS1;PNLIPRP1;ADSSL1;PRDX6;URAH;CEPT1;ITPK1;PLA2G12B
RNA polymerasePOLR3B;POLR2EB;POLR2B;POLR1C;POLR2GL;POLR3D;POLR1A;POLR1D;POLR2J2
Cytosolic DNA-sensing pathwayPOLR3B;IKBKE;POLR1C;RELA;POLR2H;AIM2;IFNA12;POLR3GL;POLR3GLB
Huntingtons diseaseUCP1;NDUFS6;SP1;CREB3L3;NDUFB6;VDAC2;TBPL2;DNAHC8;NDUFA5
Epstein-Barr virus infectionPSMD4;ENTPD1;HDAC2;PIK3R5;MAPK9;EIF2AK2;CD44;PIK3CD;HSPA2

POLR2F has several biochemical functions, for example, DNA binding, contributes_to RNA polymerase I activity, contributes_to RNA polymerase II activity. Some of the functions are cooperated with other proteins, some of the functions could acted by POLR2F itself. We selected most functions POLR2F had, and list some proteins which have the same functions with POLR2F. You can find most of the proteins on our site.

Function Related Protein
DNA bindingZNF71;SNAPC3;PROX1A;ARNTL2;LBR;SP4;ZFP36L1;HIST2H2BE;SIX4
contributes_to RNA polymerase I activityPOLR2L;POLR1E;POLR1A;POLR2EB;POLR2F;ZNRD1;POLR1C;POLR2K;TWISTNB
contributes_to RNA polymerase II activityPOLR2L;POLR2F;POLR2H;POLR2J;POLR2B;POLR2EB;POLR2J3;POLR2K;POLR2A
contributes_to RNA polymerase III activityPOLR3GL;POLR3F;POLR2E;POLR3H;POLR3E;POLR2L;POLR1D;POLR3B;POLR1C

POLR2F has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POLR2F here. Most of them are supplied by our site. Hope this information will be useful for your research of POLR2F.

MED19; MED26; BDP1; POLR2B; POLR2H; POLR3G; SDC2; IL15RA; GCOM1; MAP3K4; SUPT5H; POLR3A; POLR1C; CD3EAP; MAST3; CRCP; RECQL5

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