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Official Full Name
peptidylprolyl isomerase B (cyclophilin B)
The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.
Cphn2; Cphn-2; CyP-20b; AA408962; AA553318; AI844835