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PRPS1L1

Official Full Name

phosphoribosyl pyrophosphate synthetase 1-like 1
Overview

This intronless gene is specifically expressed in the testis, and encodes a protein that is highly homologous to the two subunits of phosphoribosylpyrophosphate synthetase encoded by human X-linked genes, PRPS1 and PRPS2. These enzymes convert pyrimidine, purine or pyridine bases to the corresponding ribonucleoside monophosphates. In vitro transcription/translation and site-directed mutagenesis studies indicate that translation of this mRNA initiates exclusively at a non-AUG (ACG) codon.
Synonyms

PRPS1L1; phosphoribosyl pyrophosphate synthetase 1-like 1; PRPSL; ribose-phosphate pyrophosphokinase 3; PRPS3; Phosphoribosyl pyrophosphate synthetase 1 like 1; Phosphoribosyl pyrophosphate synthetase III; Phosphoribosylpyrophosphate synthetase 1-like 1; Phosphoribosylpyrophosphate synthetase 3; PRPS1; PRPS1 like 1; PRS III; PRSIII; Ribose phosphate pyrophosphokinase 3; Ribose phosphate pyrophosphokinase III; Ribose-phosphate pyrophosphokinase; PRPS1-like 1; OTTHUMP00000202305; ribose-phosphate pyrophosphokinase III; phosphoribosyl pyrophosphate synthase III; phosphoribosyl pyrophosphate synthase 1-like 1; phosphoribosylpyrophosphate synthetase subunit III; ribose-; PRS-III;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PRPS1L1-1983H	Recombinant Human PRPS1L1, GST-tagged	E.coli	GST	1-318aa	$319 / 25ug
Human	PRPS1L1-504HCL	Recombinant Human PRPS1L1 lysate	HEK293	N/A		Inquiry
Human	PRPS1L1-3722H	Recombinant Human PRPS1L1 protein, His-tagged	E.coli	His	1-318 aa	$319 / 25ug

Involved Pathway
Protein Function
Interacting Protein

PRPS1L1 involved in several pathways and played different roles in them. We selected most pathways PRPS1L1 participated on our site, such as Pentose phosphate pathway, Purine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRPS1L1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Pentose phosphate pathway	DERA;PGLS;ALDOA;PRPS1L1;RGN;G6PD;PFKL;GPI;GPIB
Purine metabolism	PDE7B;POLR2J3;IMPDH1A;ENTPD3;ENTPD4;PDE8B;PAPSS2;POLR2L;ADSS
Metabolic pathways	UCK2A;PSAT1;GRHPRB;ATP6V0A1;SEPHS1;Atp5g2;AGL;PCCB;CERS5
Carbon metabolism	ME2;GOT2B;CPS1;PGAM1;PFKP;GAPDH;EHHADH;GOT1;HAO1
Biosynthesis of amino acids	PKMA;TPI1B;PCXB;TKTL2;PC;OTC;ALDOC;IDH3G;ALDOAB

PRPS1L1 has several biochemical functions, for example, ATP binding, kinase activity, magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PRPS1L1 itself. We selected most functions PRPS1L1 had, and list some proteins which have the same functions with PRPS1L1. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	UBE2NA;SMARCA4;MYO5C;SRX1;PRKCBB;CAMK2B1;ABCB3L1;DSTYK;CDC6
kinase activity	TRIOA;FYNA;NIM1;cka1;NME2A;STK30;AKT2L;BMPR2A;CKBA
magnesium ion binding	RPS6KA5;WEE2;RPS6KA3;NT5C3L;MAP2K7;PPA2;HACL1;NUDT16;PKM
protein homodimerization activity	NR6A1;CLIC6;LSM1;ODZ4;JUP;S100A16;ATIC;TRIM5;CHEK2
ribose phosphate diphosphokinase activity	PRPS2;PRPS1B;PRPS1A;PRPS1;PRPS1L1;PRPSAP1

PRPS1L1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRPS1L1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRPS1L1.