ADKB
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Zebrafish | ADKB-9837Z | Recombinant Zebrafish ADKB | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
ADKB involved in several pathways and played different roles in them. We selected most pathways ADKB participated on our site, such as Purine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADKB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Purine metabolism | TM9SF1;AK1;RRM2B;PFAS;GMPR;NME6;GUK1;PDE4B;POLE2 |
Metabolic pathways | GDA;ATP5G3A;PLCG1;P4HA1;PPAT;ATP5H;CYP3A65;MAN1C1;DNMT3A |
ADKB has several biochemical functions, for example, adenosine kinase activity, kinase activity, phosphotransferase activity, alcohol group as acceptor. Some of the functions are cooperated with other proteins, some of the functions could acted by ADKB itself. We selected most functions ADKB had, and list some proteins which have the same functions with ADKB. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
adenosine kinase activity | ADKA;ADKB;ADK |
kinase activity | TAB3;GKUP;NLK1;CDK5R1;PKN2;GSK3AB;TLK1B;MAP4K6;FAM20B |
phosphotransferase activity, alcohol group as acceptor | PI4KAA;PI4KAP2;G6PC;FAM20B;PI4KAB;POMK;ADKA;SMG1;SGK196 |
transferase activity | PRDM6;UGT1A5;GXYLT2;NDUFAF6;SAT2B;ST3GAL3B;MCAT;NME2B.1;ZDHHC6 |
ADKB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADKB here. Most of them are supplied by our site. Hope this information will be useful for your research of ADKB.
- Q&As
- Reviews
Q&As (15)
Ask a questionADKB inhibitors are being investigated for a variety of other diseases, including cardiovascular disease, neurological disorders, and metabolic disorders such as diabetes. For example, studies have shown that ADKB inhibitors can improve glucose metabolism and insulin sensitivity in animal models of diabetes. Additionally, ADKB has been implicated in the development of neurodegenerative diseases such as Alzheimer's and Parkinson's disease, and ADKB inhibitors are being tested as potential treatments for these conditions.
Yes, ADKB is considered a druggable target, meaning that it can be targeted with small molecule drugs. Several ADKB inhibitors have been developed and are currently being tested in preclinical and clinical studies for a variety of conditions. However, further research is needed to determine the efficacy and safety of these inhibitors for different diseases.
Yes, there are some natural products that have been shown to inhibit ADKB. These include curcumin, a compound found in turmeric, and resveratrol, a compound found in grapes and red wine. However, the levels of ADKB inhibition achieved with these natural products may not be as potent as those achieved with synthetic inhibitors, and further research is needed to determine their efficacy as ADKB inhibitors.
Yes, like all medications, ADKB inhibitors can have side effects. The specific side effects can vary depending on the inhibitor used, the dose, and the individual's response to the medication. Common side effects of ADKB inhibitors can include nausea, vomiting, diarrhea, fatigue, and muscle cramps. In some cases, ADKB inhibitors can also cause more serious side effects such as blood disorders, liver damage, and heart problems.
ADKB levels have been found to be decreased in patients with mitochondrial disorders, suggesting that it may be a useful biomarker for these conditions. However, further research is needed to determine its specificity and sensitivity as a diagnostic marker.
ADKB inhibitors can be administered orally in the form of pills or capsules. In some cases, they may also be administered intravenously (through an IV infusion). Dosage and administration will vary depending on the specific inhibitor and the condition being treated. It is important to follow the instructions of a healthcare provider when taking ADKB inhibitors, and to report any potential side effects or concerns promptly.
No, ADKB inhibitors are not effective for all types of cancer. They are most commonly used to treat certain types of leukemia and solid tumors such as gastrointestinal stromal tumors (GISTs). However, ADKB inhibitors are not effective for all cases of these cancers, and they may not be effective for other types of cancer. The use of ADKB inhibitors in cancer treatment is an area of ongoing research and development.
Yes, there are currently FDA-approved drugs that act as ADKB inhibitors. These include Imatinib (Gleevec) and Dasatinib (Sprycel), which are both used to treat certain types of leukemia. These drugs were initially developed as inhibitors of a different kinase, but were found to also inhibit ADKB. However, their use as ADKB inhibitors for other conditions is still being investigated in preclinical and clinical studies.
Yes, ADKB has been linked to several neurological disorders, including Parkinson's disease and Alzheimer's disease. Studies have shown that ADKB levels are decreased in the brains of patients with these conditions, suggesting that it may play a role in their pathogenesis. Additionally, ADKB has been shown to regulate the dynamics of mitochondria in neurons, which is critical for neuronal function.
ADKB expression has been found to be dysregulated in several types of cancer, including breast, prostate, and pancreatic cancer. It has been shown to promote cancer cell survival and proliferation by regulating energy metabolism and signaling pathways. ADKB inhibitors have been developed as potential anticancer agents, and some have shown efficacy in preclinical models.
ADKB inhibitors have been studied as a potential therapeutic strategy for cancer, particularly in combination with other therapies such as chemotherapy or radiation therapy. They have shown promise in preclinical models by inhibiting cancer cell growth and inducing cell death. However, further research is needed to determine their safety and efficacy in clinical trials.
Yes, ADKB has been identified as a potential therapeutic target for metabolic disorders such as obesity and type 2 diabetes. Studies have shown that ADKB levels are elevated in the skeletal muscle of obese individuals and that ADKB inhibitors can improve insulin sensitivity in animal models of type 2 diabetes. Further research is needed to determine the efficacy of ADKB inhibitors for these conditions in human studies.
Yes, ADKB inhibitors have potential applications for a variety of conditions beyond cancer. For example, they have been studied as a potential treatment for sickle cell anemia, which involves the destruction of red blood cells and reduced oxygen transport. ADKB inhibitors have been shown to increase the production of a molecule called 2,3-BPG, which can improve the oxygen transport capacity of red blood cells.
Yes, like all drugs, ADKB inhibitors can cause side effects. The specific side effects can vary depending on the drug and the dose used. Common side effects include nausea, vomiting, diarrhea, fatigue, and skin rash. More serious side effects can also occur, such as liver toxicity, fluid retention, and cardiovascular events. It is important to discuss the potential side effects with a healthcare provider before starting treatment with an ADKB inhibitor.
Yes, ADKB inhibitors have been investigated as potential cancer treatments. ADKB plays a role in promoting the growth and survival of cancer cells, particularly in certain types of leukemia and solid tumors. Inhibiting ADKB can lead to decreased cancer cell growth and increased cell death. Imatinib and Dasatinib, which were mentioned earlier, are commonly used as ADKB inhibitors in the treatment of leukemia.
Customer Reviews (3)
Write a reviewI believe this protein will meet all of my experimental needs.
It is highly pure and shows excellent activity in my assays.
the manufacturer's technical support team has been incredibly helpful and responsive, providing me with excellent support that has solved any issues I encountered during my experiments.
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