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AMELY

  • Official Full Name

    AMELY amelogenin, Y-linked [ Homo sapiens ]

  • Overview

    This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in a related gene on chromosome X cause X-linked amelogenesis imperfecta.
  • Synonyms

    Amelogenin (Y chromosome); Amelogenin; Amelogenin Y isoform; Amelogenin Y linked; AMELY; AMELY_HUMAN; AMGL; AMGY; Y isoform;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human AMELY-9613H Recombinant Human AMELY, GST-tagged E.coli GST 17-192a.a.
Human AMELY-9645H Recombinant Human AMELY protein, MYC/DDK-tagged HEK293 Myc/DDK
Human AMELY-457H Recombinant Human AMELY Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human AMELY-1503HFL Recombinant Full Length Human AMELY protein, Flag-tagged Mamanlian cells Flag
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • AMELY Related Articles

AMELY involved in several pathways and played different roles in them. We selected most pathways AMELY participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AMELY were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

AMELY has several biochemical functions, for example, structural constituent of tooth enamel. Some of the functions are cooperated with other proteins, some of the functions could acted by AMELY itself. We selected most functions AMELY had, and list some proteins which have the same functions with AMELY. You can find most of the proteins on our site.

Function Related Protein
structural constituent of tooth enamelAMELX;TUFT1;AMBN;AMELY;STATH

AMELY has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMELY here. Most of them are supplied by our site. Hope this information will be useful for your research of AMELY.

Qi, LX; Wang, L; et al. Activated amelogenin Y-linked (AMELY) regulation and angiogenesis in human hepatocellular carcinoma by biocomputation. ONCOLOGY LETTERS 5:1075-1079(2013).
Raudsepp, T; Durkin, K; et al. Molecular heterogeneity of XY sex reversal in horses. ANIMAL GENETICS 41:41-52(2010).
  • Q&As
  • Reviews

Q&As (10)

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How does AMELY contribute to tooth morphogenesis and differentiation? 08/22/2022

AMELY is involved in tooth morphogenesis and differentiation by regulating the proliferation, differentiation, and mineralization processes during odontogenesis.

How does AMELY expression differ between male and female individuals? 12/12/2021

AMELY expression is specific to male individuals and absent in females.

What are the molecular mechanisms underlying AMELY gene regulation during dental development? 06/01/2021

The regulation of AMELY gene expression during dental development involves intricate interactions between transcription factors, hormonal signals, and genetic cascades.

What are the functional consequences of AMELY mutations or deletions in dental development? 11/04/2020

Mutations or deletions in the AMELY gene can lead to dental abnormalities, specifically affecting male dental development, such as variations in tooth morphology or function.

How does AMELY interact with other dental-specific proteins or signaling pathways? 11/02/2020

AMELY interacts with other dental-specific proteins and signaling pathways, influencing tooth germ development, dental epithelial-mesenchymal interactions, and the formation of male-specific dental structures.

How does AMELY influence odontogenesis processes, such as tooth crown morphology and tissue differentiation? 12/28/2019

AMELY contributes to odontogenesis by influencing tooth crown morphology, establishing tooth shape, size, and structural organization characteristic of male dentition.

Can manipulating AMELY expression or activity provide potential strategies for treating male dental abnormalities or developing gender-specific dental interventions? 07/20/2019

Manipulating AMELY expression or activity holds potential for developing therapeutic strategies targeting male dental abnormalities or gender-specific dental interventions, such as cosmetic dentistry or orthodontic treatments.

What is the role of AMELY in male-specific dental development? 03/29/2019

AMELY plays a crucial role in male-specific dental development, contributing to the formation and differentiation of dental tissues that exhibit sexual dimorphism.

What are the post-translational modifications of AMELY and their significance in dental development? 06/21/2018

AMELY undergoes post-translational modifications, including phosphorylation and glycosylation, which may impact its stability, localization, and interactions with other proteins involved in dental development and differentiation.

How does AMELY impact the molecular pathways involved in tooth mineralization and tissue maturation? 02/14/2018

AMELY influences molecular pathways related to tooth mineralization and tissue maturation, participating in the regulation of dental matrix formation, enamel mineralization, and dentinogenesis processes.

Customer Reviews (3)

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Reviews
01/02/2022

    Enhanced assay sensitivity for detection of subtle protein changes.

    04/19/2019

      Compatibility with complex biological matrices for translational research.

      07/07/2017

        Accurate determination of protein function and activity.

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