AMELY
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Official Full Name
AMELY amelogenin, Y-linked [ Homo sapiens ]
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Overview
This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in a related gene on chromosome X cause X-linked amelogenesis imperfecta. -
Synonyms
Amelogenin (Y chromosome); Amelogenin; Amelogenin Y isoform; Amelogenin Y linked; AMELY; AMELY_HUMAN; AMGL; AMGY; Y isoform;
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | AMELY-9613H | Recombinant Human AMELY, GST-tagged | E.coli | GST | 17-192a.a. | |
Human | AMELY-9645H | Recombinant Human AMELY protein, MYC/DDK-tagged | HEK293 | Myc/DDK | ||
Human | AMELY-457H | Recombinant Human AMELY Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK | ||
Human | AMELY-1503HFL | Recombinant Full Length Human AMELY protein, Flag-tagged | Mamanlian cells | Flag |
- Involved Pathway
- Protein Function
- Interacting Protein
- AMELY Related Articles
AMELY involved in several pathways and played different roles in them. We selected most pathways AMELY participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AMELY were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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AMELY has several biochemical functions, for example, structural constituent of tooth enamel. Some of the functions are cooperated with other proteins, some of the functions could acted by AMELY itself. We selected most functions AMELY had, and list some proteins which have the same functions with AMELY. You can find most of the proteins on our site.
Function | Related Protein |
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structural constituent of tooth enamel | AMELX;TUFT1;AMBN;AMELY;STATH |
AMELY has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMELY here. Most of them are supplied by our site. Hope this information will be useful for your research of AMELY.
- Q&As
- Reviews
Q&As (10)
Ask a questionAMELY is involved in tooth morphogenesis and differentiation by regulating the proliferation, differentiation, and mineralization processes during odontogenesis.
AMELY expression is specific to male individuals and absent in females.
The regulation of AMELY gene expression during dental development involves intricate interactions between transcription factors, hormonal signals, and genetic cascades.
Mutations or deletions in the AMELY gene can lead to dental abnormalities, specifically affecting male dental development, such as variations in tooth morphology or function.
AMELY interacts with other dental-specific proteins and signaling pathways, influencing tooth germ development, dental epithelial-mesenchymal interactions, and the formation of male-specific dental structures.
AMELY contributes to odontogenesis by influencing tooth crown morphology, establishing tooth shape, size, and structural organization characteristic of male dentition.
Manipulating AMELY expression or activity holds potential for developing therapeutic strategies targeting male dental abnormalities or gender-specific dental interventions, such as cosmetic dentistry or orthodontic treatments.
AMELY plays a crucial role in male-specific dental development, contributing to the formation and differentiation of dental tissues that exhibit sexual dimorphism.
AMELY undergoes post-translational modifications, including phosphorylation and glycosylation, which may impact its stability, localization, and interactions with other proteins involved in dental development and differentiation.
AMELY influences molecular pathways related to tooth mineralization and tissue maturation, participating in the regulation of dental matrix formation, enamel mineralization, and dentinogenesis processes.
Customer Reviews (3)
Write a reviewEnhanced assay sensitivity for detection of subtle protein changes.
Compatibility with complex biological matrices for translational research.
Accurate determination of protein function and activity.
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