CACNG6
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Official Full Name
calcium channel, voltage-dependent, gamma subunit 6
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Synonyms
CACNG6;calcium channel, voltage-dependent, gamma subunit 6;13625;ENSG00000130433;19q13.4;voltage-dependent calcium channel gamma-6 subunit;voltage-dependent calcium channel gamma-6 subunit;neuronal voltage-gated calcium channel gamma-6 subunit;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- E.coli expression system
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- Fc
- Avi
- Myc
- DDK
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
CACNG6 involved in several pathways and played different roles in them. We selected most pathways CACNG6 participated on our site, such as MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, which may be useful for your reference. Also, other proteins which involved in the same pathway with CACNG6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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MAPK signaling pathway | SOS1;PPP3CC;FGF19;NFATC1;PPM1B;FGFR3;TAOK1;NTRK2B;NF1 |
Cardiac muscle contraction | ATP1A3B;COX8A;ATP1B2;ATP1A2A;COX6A2;VMHCL;TNNC1A;SLC8A1;CACNA2D2 |
Adrenergic signaling in cardiomyocytes | CACNG6A;CAMK2D;CALML5;CAMK2B1;TNNT2;TPM4A;PPP1CA;TNNI3;SCN1BB |
Oxytocin signaling pathway | RYR2;PRKAG1;PIK3R1;ACTG1;PLCB1;NFATC1;PTGS2;PRKACG;GUCY1B3 |
Hypertrophic cardiomyopathy (HCM) | IGF1;CACNB3;ITGA9;TPM1;MYH7;CACNG8;CACNA2D4;TNNI3;MYL3 |
Arrhythmogenic right ventricular cardiomyopathy (ARVC) | ITGB5;ITGB3;DSC2;ATP2A2;CACNG1;TCF7;ITGB4;CACNB4;CTNNA3 |
Dilated cardiomyopathy | ITGB6;ITGB3;ITGA5;MYL3;CACNA2D4;ADRB1;ITGA8;RYR2;SLC8A1 |
CACNG6 has several biochemical functions, for example, voltage-gated calcium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CACNG6 itself. We selected most functions CACNG6 had, and list some proteins which have the same functions with CACNG6. You can find most of the proteins on our site.
Function | Related Protein |
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voltage-gated calcium channel activity | CACNG7;CACNA1BA;CACNG3;CACNG1A;CACNB4B;CATSPER1;CALHM1;CACNA2D4;ATP6V0CB |
CACNG6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CACNG6 here. Most of them are supplied by our site. Hope this information will be useful for your research of CACNG6.
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Q&As (7)
Ask a questionDysfunctions or mutations in CACNG6 have been suggested in certain neurological conditions, but further research is essential for direct associations.
Genetic alterations in the CACNG6 gene can modify its modulatory role, potentially impacting the function and behavior of linked calcium channels.
CACNG6 serves as an auxiliary subunit, assisting in the modulation of activity, trafficking, and surface expression of voltage-gated calcium channels.
Through its interaction, CACNG6 can influence the channel's gating properties, its cellular localization, and calcium ion permeation.
CACNG6 is primarily found in neural tissues, notably within the brain.
CACNG6 interacts mainly with the alpha-1 subunit of calcium channels, and it might also bind to other proteins within the channel complex.
Specific methods, such as mass spectrometry, might be employed to detect potential post-translational modifications on CACNG6.
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