Active Recombinant Canine MET Protein, His-tagged
Cat.No. : | MET-1037C |
Product Overview : | Recombinant extracellular domain of canine MET (NP_001002963.1) (Met 1-Leu 935) was expressed, with a polyhistidine tag at the N-terminus. |
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Source : | HEK293 |
Species : | Canine |
Tag : | His |
Predicted N Terminal : | Glu 25 |
Form : | Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol. |
Bio-activity : | 1. Measured by its binding ability in a functional ELISA. 2. Immobilized human HGF at 10 μg/mL (100 μl/well) can bind canine c-MET, The EC50 of canine c-MET is 7 ng/mL. 3. Immobilized canine MET-His at 10 μg/ml (100 μl/well) can bind biotinylated human HG |
Molecular Mass : | The recombinant canine c-Met is a disulfide-linked heterodimer composed of proteolytically cleaved α and β subunits. Each α and β subunit together consists of 922 amino acids and has a predicted molecular mass of 103 (α =33 + β =70) kDa. As a result of glycosylation, the apparent molecular mass of the canine c-Met is approximately 42-47 kDa and 85-95 kDa respectively in SDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >95 % as determined by SDS-PAGE. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Protein length : | Met1-Leu935 |
Gene Name : | MET MET proto-oncogene, receptor tyrosine kinase [ Canis lupus familiaris ] |
Official Symbol : | MET |
Synonyms : | c-Met; HGF receptor; HGF/SF receptor; SF receptor; met proto-oncogene (hepatocyte growth factor receptor); met proto-oncogene tyrosine kinase; proto-oncogene c-Met; scatter factor receptor; tyrosine-protein kinase Met |
Gene ID : | 403438 |
mRNA Refseq : | NM_001002963 |
Protein Refseq : | NP_001002963 |
MIM : | |
UniProt ID : | Q75ZY9 |
Chromosome Location : | chromosome: 14 |
Pathway : | Adherens junction, organism-specific biosystem; Axon guidance, conserved biosystem; Central carbon metabolism in cancer, organism-specific biosystem |
Function : | ATP binding; transmembrane receptor protein tyrosine kinase activity |
Products Types
◆ Recombinant Protein | ||
MET-4419H | Recombinant Human MET Protein, GST-tagged | +Inquiry |
MET-33H | Active Recombinant Human MET (R1227K) Protein (956-end), N-GST tagged | +Inquiry |
MET-6744H | Recombinant Human MET protein, His-tagged, Site-Specific AF 488-Labeled | +Inquiry |
Met-1773M | Recombinant Mouse Met Protein, His-tagged | +Inquiry |
MET-289H | Recombinant Human MET Protein, His-tagged | +Inquiry |
◆ Lysates | ||
MET-1931CCL | Recombinant Canine MET cell lysate | +Inquiry |
MET-1054RCL | Recombinant Rat MET cell lysate | +Inquiry |
MET-001CCL | Recombinant Cynomolgus MET cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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