Active Recombinant Human NTRK3 Protein, His-tagged
Cat.No. : | NTRK3-161H |
Product Overview : | Human TrkC / NTRK3 Protein (Human TrkC, His Tag) Cys 32 - Thr 429 (Accession # AAH13693.1) was produced in human 293 cells (HEK293). |
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Source : | HEK293 |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Cys 32 |
Form : | Lyophilized from sterile PBS, pH7.4, 10% Trehalose. |
Bio-activity : | Measured by its ability to inhibit NT-3-induced proliferation of BaF-TrkB-BD mouse pro-B cells transfected with TrkB. The ED50 for this effect is typically 0.01 - 0.1 ug/mL in the presence of 40 ng/mL of recombinant human NT-3. |
Molecular Mass : | Human TrkC, His Tag is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 45.6 kDa. The reducing protein migrates as 80-90 kDa in SDS-PAGE due to glycosylation. |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Protein length : | Cys32-Thr429 |
Gene Name : | NTRK3 neurotrophic tyrosine kinase, receptor, type 3 [ Homo sapiens ] |
Official Symbol : | NTRK3 |
Synonyms : | NTRK3; neurotrophic tyrosine kinase, receptor, type 3; NT-3 growth factor receptor; TRKC; GP145-TrkC; ETV6-NTRK3 fusion; tyrosine kinase receptor C; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; gp145(trkC); |
Gene ID : | 4916 |
mRNA Refseq : | NM_001007156 |
Protein Refseq : | NP_001007157 |
MIM : | 191316 |
UniProt ID : | Q16288 |
Chromosome Location : | 15q24-q25 |
Pathway : | Neurotrophic factor-mediated Trk receptor signaling, organism-specific biosystem; Neurotrophin signaling pathway, organism-specific biosystem; Neurotrophin signaling pathway, conserved biosystem; |
Function : | ATP binding; neurotrophin binding; nucleotide binding; receptor activity; transmembrane receptor protein tyrosine kinase activity; |
Products Types
◆ Recombinant Protein | ||
NTRK3-3765R | Recombinant Rat NTRK3 Protein, His (Fc)-Avi-tagged | +Inquiry |
NTRK3-4468H | Recombinant Human NTRK3 Protein, His (Fc)-Avi-tagged | +Inquiry |
NTRK3-380H | Recombinant Human NTRK3 Protein, His-tagged | +Inquiry |
Ntrk3-009M | Recombinant Mouse Ntrk3 Protein, His-tagged | +Inquiry |
Ntrk3-035M | Recombinant Mouse Ntrk3 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
NTRK3-2825HCL | Recombinant Human NTRK3 cell lysate | +Inquiry |
NTRK3-2583MCL | Recombinant Mouse NTRK3 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1632 | U2OS TrkC Bioassay Kit | +Inquiry |
Kit-1633 | TrkC Functional Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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