Active Recombinant Human OSM protein

• Cat.No.: OSM-2106H
• Product Overview: Recombinant Human OSM protein(NP_065391.1)(Ala 26 - Arg 252) was expressed in HEK293.

Specification

• Source: HEK293
• Species: Human
• Tag: Non
• Form: PBS, pH7.4
• Bio-activity: Immobilized Human Oncostatin M, Tag Free at 5 μg/mL (100 μL/well) can bind Human LIF R, Fc Tag with a linear range of 0.01-0.156 μg/mL.
• Molecular Mass: 25.8 kDa
• Protein length: Ala 26 - Arg 252
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: This product is stable after storage at:
  -20°C to -70°C for 12 months in lyophilized state;
  -70°C for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended to reconstitute the lyophilized powder in sterile water to 100-200 ug/ml, and further dilute with other solvents. The dissolved protein can be stored at 4°C for 2-7 days and should be used up as soon as possible. If not in use for a short time, please store at -20°C.

Gene Information

• Gene Name: OSM oncostatin M [ Homo sapiens ]
• Official Symbol: OSM
• Synonyms: OSM; oncostatin M; oncostatin-M; MGC20461
• Gene ID: 5008
• mRNA Refseq: NM_020530
• Protein Refseq: NP_065391
• MIM: 165095
• UniProt ID: P13725

Reviews

11/25/2020

Outstanding protein-protein interaction studies, vital for our projects.

03/02/2020

High-quality protein characterization, fundamental for our experiments.

02/27/2019

Expertise in peptide synthesis, accelerates our peptide-based research.

Q&As

What is the impact of OSM on cancer development and progression, particularly in terms of tumor microenvironment modulation?

OSM can influence cancer progression by altering the tumor microenvironment and affecting tumor cell behavior.

How does OSM (Oncostatin M) regulate inflammatory and immune responses in the body?

OSM plays a key role in regulating inflammatory and immune responses, modulating cytokine production and immune cell activity.

How does OSM contribute to wound healing and tissue regeneration processes?

OSM aids in wound healing and tissue regeneration, promoting cell growth and repair mechanisms.

What role does OSM play in the pathogenesis of autoimmune diseases like rheumatoid arthritis?

OSM is implicated in autoimmune diseases, contributing to inflammation and joint damage in conditions like rheumatoid arthritis.

How does OSM influence liver fibrosis and hepatic diseases?

OSM is involved in liver fibrosis, impacting the development and progression of hepatic diseases.

What are the mechanisms by which OSM modulates cellular growth, differentiation, and apoptosis?

OSM regulates cellular processes like growth, differentiation, and apoptosis, affecting various tissue functions.

How do alterations in OSM expression or signaling affect cardiovascular health and disease?

Changes in OSM signaling can impact cardiovascular health, influencing disease development and progression.