Active Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD (N501Y) Protein, Fc-tagged
Cat.No. : | S-425S |
Product Overview : | Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD (YP_009724390.1, with mutation N501Y) (Arg319-Phe541) was expressed in HEK293 cell with the Fc region of human IgG1 at the C-terminus. The mutation were identified in the SARS-CoV-2 variant (known as 20B/501Y.V1, VOC 202012/01, or B.1.1.7 lineage) which emerged in the United Kindom. |
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Source : | HEK293 |
Species : | SARS-CoV-2 |
Tag : | Fc |
Predicted N Terminal : | Ser |
Bio-activity : | Measured by its binding ability in a functional ELISA. Immobilized human ACE2 protein (His tag) at 2μg/mL (100μL/well) can bind S3-2019-nCov-2-RBD(319R-541F,N501Y)-Fc, the EC50 of S3-2019-nCov-2-RBD(319R-541F,N501Y)-Fc is 1.5-8.0 ng/mL. |
Molecular Mass : | The recombinant SARS-CoV-2 (2019-nCoV) Spike RBD consists of 462 amino acids and predicts a molecular mass of 52 kDa. As a result of glycosylation, it migrates as an approximately 57 kDa band in SDS-PAGE under reducing conditions. |
Protein length : | 319-541 |
Endotoxin : | < 1.0 EU/μg protein as determined by the LAL method. |
Purity : | > 90 % as determined by SDS-PAGE. |
Storage : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. |
Gene Name : | S surface glycoprotein [ Severe acute respiratory syndrome coronavirus 2 ] |
Official Symbol : | S |
Synonyms : | S; surface glycoprotein; spike glycoprotein; surface glycoprotein; structural protein; spike protein |
Gene ID : | 43740568 |
mRNA Refseq : | MN908947 |
Protein Refseq : | YP_009724390 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Please let me know the sequence part you deleted or the whole aa region of this peptide
08/09/2023
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