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Recombinant Human PDK2, His-tagged

Cat.No. : PDK2-651H
Product Overview : Recombinant Human PDK2 with a His tag is expressed inBacteriaand column-purified.
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  • Gene Information
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Cat. No. : PDK2-651H
Description : PDH kinases (PDK"s) deactivate PDH by reversible phosphorylation. In humans and rodents, 4 PDK"s are present in an organ-dependent manner. In all cases, PDK"s are physically part of the PDH complex (binding via lipoyl domain 2 of E2), and they phosphorylate the E1 subunit at 3 specific serine residues. PDH phosphatases remove the phosphorylation and restore activity of PDH.
Source : Bacteria.
Storage : Store at -80°C.
Gene Name : PDK2 pyruvate dehydrogenase kinase, isozyme 2 [ Homo sapiens ]
Synonyms : PDK2; pyruvate dehydrogenase kinase, isozyme 2; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial; pyruvate dehydrogenase kinase, isoenzyme 2; pyruvate dehydrogenase, lipoamide, kinase isozyme 2, mitochondrial; PDHK2; EC 2.7.11.2
Gene ID : 5164
mRNA Refseq : NM_002611
Protein Refseq : NP_002602
MIM : 602525
UniProt ID : Q15119
Chromosome Location : 17q21.33
Pathway : Integration of energy metabolism; Pyruvate metabolism and Citric Acid (TCA) cycle
Function : ATP binding; nucleotide binding; protein heterodimerization activity; pyruvate dehydrogenase (acetyl-transferring) kinase activity; protein homodimerization activity; transferase activity; two-component sensor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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