Recombinant Dengue Virus Serotype 4 VLP

Cat.No. : VLP-04D
Product Overview : Recombinant Dengue Virus serotype 4 virus-like particle recombinant antigen consisting of Envelope, pre-Membrane and Membrane protein produced in 293 human cells. The Cterminal 20% of the dengue Envelope protein was replaced by the corresponding Japanese encephalitis virus SA-14 sequence (Envelope protein amino acids 400-495). The replaced sequence corresponds to the transmembrane and intraparticle portion of the protein.
Strain/Isolate: Dominica/814669/1981
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Description : Virus-Like Particles (VLPs) are an emerging vaccine technology. VLPs consist of protein shells comprising outer proteins specific to the virus in question. VLPs are more representative of how viral antigens are presented in vivo and while they are highly immunogenic they are non-infectious as they lack the core genetic material of the virus. Another important advantage of VLPs is that they more effectively activate key aspects of the immune response to achieve potent immune stimulation and to provide immunological memory. VLP-based vaccines have also shown to provide effective protection and are in current use for several diseases and in development for many others.
Source : HEK293
Species : Dengue Virus Serotype 4
Form : Liquid
Purity : > 95% by SDS-PAGE
Stability : At +4 centigrade: 1 week
At -80 centigrade: 1 year
Avoid excessive mixing or shocking to prevent aggregation. Long term storage above -80 centigrade may result in aggregate formation.
Can be frozen, but avoid multiple freeze/thaw cycles.
Storage : Short Term Storage: +4 centigrade
Long Term Storage: -80 centigrade
Storage Buffer : Dulbecco’s PBS pH7.4, 30% sucrose
Shipping : Dry ice.
Synonyms : VLP; virus-like particles
Synonyms : VLP; virus-like particles

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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