Recombinant Full Length Xenopus Laevis Fibroblast Growth Factor Receptor 2(Fgfr2) Protein, His-Tagged

• Cat.No.: RFL9320XF
• Product Overview: Recombinant Full Length Xenopus laevis Fibroblast growth factor receptor 2(fgfr2) Protein (Q03364) (15-813aa), fused to N-terminal His tag, was expressed in E. coli.

Specification

• Source: E.coli expression system
• Species: Xenopus laevis (African clawed frog)
• Tag: His
• Form: Lyophilized powder
• Protein length: Full Length of Mature Protein (15-813)
• AA Sequence: TIARPSYSMVDDTTPEPEEPPAKYQ ISKADVFPVLPGEPLDLRCPLADGP LVTWTKDGAKLEVNNRTLIVRTYLQ IKESTTRDSGLYACSVLKNSHFFHV NVTEASSSGDDEDDNDGSEDFTNDN NNIRAPYWTNTEKMEKKLHAVSAAN TVKLRCPAREPHPSNEWLKNGKEFK QEHRIGGYKVRNQHWSLIMESVVPS DKGIYTCIVENEHGSINHTYHLDVI ERSSHRPILQAGLPANTTAVVGGDA EFVCKVYSDAQPHIRWVRYIEKNGS RFGVDGLPYFKVLKAAGVNVTDEEI EVLYVRNVSFEDAGEYTCIAGNSIG ISQHSAWLTVHPAPVNPLEDNPVPY YMEIGIYSTGIFIIFCMVVVCVVCR MRQGAKKKKNFTGPPVHKLTKRIPL HRQVTVSADSSSSMNSTTPLVRITT RLLNSTDAMPLANVSEYELPHDPMW EFSRDKLTLGKPLGEGCFGQVVMAE ALGIDKERPKESVTVAVKMLKDNAT EKDLADLVSEMEMMKMIGKHKNIIN LLGACTQGGTLYVIVEYAAKGNLRQ YLRARRPLEMEYSFDVTRVPDEQMT FKDLVSCTYQIARGMEYLASQKCIH RDLAARNVLVTENNVMKIADFGLAR DVNNIDYYKKTSNGRLPVKWMAPEA LFDRVYTHQSDVWSFGVLMWEIFTL GGSPYPGIPVEELFKLLKEGHRMDK PANCTNELYMMMRDCWHAIPSHRPT FKQLVEDLDRILTLTTNEEYLDLSA PLEQYSPSFPDSSCSASSSSGDDSV FSPDPMPHDPCLPKFQHVNGVVKT
• Purity: Greater than 90% as determined by SDS-PAGE.
• Applications: SDS-PAGE
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Tris/PBS-based buffer, 6% Trehalose, pH 8.0
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
• Gene Name: fgfr2
• Synonyms: fgfr2; Fibroblast growth factor receptor 2; FGFR-2
• UniProt ID: Q03364

Gene Information

• Gene Name: fgfr2
• Synonyms: fgfr2; Fibroblast growth factor receptor 2; FGFR-2
• UniProt ID: Q03364

Reviews

08/24/2017

The FGFR2 protein is an outstanding product that possesses exceptional quality, making it an ideal choice for my experimental needs.

03/05/2017

What sets FGFR2 apart is the manufacturer's unparalleled technical support.

09/13/2016

The versatility of the FGFR2 protein makes it a valuable asset in my research.

Q&As

How is FGFR2 linked to developmental disorders?

Mutations in FGFR2 are associated with various developmental disorders, impacting the development of the skull, limbs, and other structures.

Can FGFR2 be targeted for personalized cancer therapy?

Yes, targeting FGFR2 mutations allows for more personalized and precise therapeutic approaches in cancer treatment.

Are there clinical trials involving FGFR2 inhibitors?

Yes, numerous clinical trials are underway to evaluate the efficacy of FGFR2 inhibitors in treating various cancers and developmental disorders.

How does FGFR2 impact wound healing?

FGFR2 is involved in the regulation of cell migration and tissue repair, contributing to the process of wound healing.

Are there any side effects associated with FGFR2 inhibitors?

Common side effects of FGFR2 inhibitors include fatigue, nausea, and hypertension, which are being studied for better management.