Recombinant Human BCL2-Like 11 (apoptosis facilitator), His-tagged
Cat.No. : | BCL2L11-6967H |
Product Overview : | Recombinant human BCL2L11 protein, fused to His-tag at N-terminus, was expressed in E. coli. |
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Description : | BCL2L11 belongs to the Bcl-2 family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The expression of BCL2L11 can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20 mM Tris-HCl buffer, pH8.0, 2M Urea, 20% glycerol 5mM DTT, 300mM NaCl. |
Molecular Mass : | 18.5 kDa (162aa) |
Protein length : | 1-138aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSHMAKQPS DVSSECDREG RQLQPAERPP QLRPGAPTSL QTEPQDRSPA PMSCDKSTQT PSPPCQAFNH YLSAMASMRQ AEPADMRPEI WIAQELRRIG DEFNAYYARR VFLNNYQAAE DHPRMVILRL LRYIVRLVWR MH |
Purity : | >80% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5mg/ml (determined by Bradford assay) |
Gene Name : | BCL2L11 BCL2-like 11 (apoptosis facilitator) [ Homo sapiens ] |
Official Symbol : | BCL2L11 |
Synonyms : | BCL2L11; BCL2-like 11 (apoptosis facilitator); bcl-2-like protein 11; BIM; BimEL; BimL; BOD; bcl2-L-11; bcl-2 interacting protein Bim; bcl-2-related ovarian death agonist; bcl-2 interacting mediator of cell death; BAM; BIM-beta6; BIM-beta7; BIM-alpha6; |
Gene ID : | 10018 |
mRNA Refseq : | NM_001204106 |
Protein Refseq : | NP_001191035 |
MIM : | 603827 |
UniProt ID : | O43521 |
Chromosome Location : | 2q13 |
Pathway : | Activation of BH3-only proteins, organism-specific biosystem; Activation of BIM and translocation to mitochondria, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members, organism-specific biosystem; Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; |
Function : | contributes_to microtubule binding; microtubule binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
BCL2L11-991M | Recombinant Mouse BCL2L11 Protein, His (Fc)-Avi-tagged | +Inquiry |
BCL2L11-618R | Recombinant Rat BCL2L11 Protein, His (Fc)-Avi-tagged | +Inquiry |
BCL2L11-3454H | Recombinant Human BCL2L11 protein, His-tagged | +Inquiry |
BCL2L11-133H | Recombinant Human BCL2L11 protein(Ala2-Arg120), His-tagged | +Inquiry |
BCL2L11-960R | Recombinant Rat BCL2L11 Protein | +Inquiry |
◆ Lysates | ||
BCL2L11-60HCL | Recombinant Human BCL2L11 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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