Recombinant Human BRAF Protein, His-tagged, BSA Conjugated
Cat.No. : | BRAF-2782H |
Product Overview : | BSA Conjugated Recombinant Human BRAF Protein (Arg726-Ala736+C) fused with a N-His tag. |
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Description : | This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. |
Source : | Protein Conjugation |
Species : | Human |
Tag : | His |
Form : | Freeze-dried powder |
Protein length : | Arg726-Ala736+C |
Purity : | > 90% |
Applications : | Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Storage Buffer : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
Reconstitution : | Reconstitute in PBS or others. |
Gene Name : | BRAF v-raf murine sarcoma viral oncogene homolog B1 [ Homo sapiens ] |
Official Symbol : | BRAF |
Synonyms : | BRAF; v-raf murine sarcoma viral oncogene homolog B1; serine/threonine-protein kinase B-raf; BRAF1; p94; 94 kDa B-raf protein; proto-oncogene B-Raf; murine sarcoma viral (v-raf) oncogene homolog B1; B-Raf proto-oncogene serine/threonine-protein kinase (p94); NS7; RAFB1; B-RAF1; FLJ95109; MGC126806; MGC138284; |
Gene ID : | 673 |
mRNA Refseq : | NM_004333 |
Protein Refseq : | NP_004324 |
MIM : | 164757 |
UniProt ID : | P15056 |
Products Types
◆ Recombinant Protein | ||
BRAF-328H | Recombinant Human BRAF Protein, His-tagged | +Inquiry |
BRAF-1081M | Recombinant Mouse BRAF Protein, His (Fc)-Avi-tagged | +Inquiry |
Braf-441M | Recombinant Mouse Braf Protein, MYC/DDK-tagged | +Inquiry |
BRAF-2781H | Recombinant Human BRAF Protein, His-tagged, BSA Conjugated | +Inquiry |
BRAF-456H | Recombinant Human BRAF Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
BRAF-8414HCL | Recombinant Human BRAF 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Please let us confirm whether or not the following kinase products marketed by your company are products applicable to the Cartagena Law in Japan.
If the product is used in Japan and falls under the Cartagena Law, it needs to be controlled appropriately.
BRAF-550H 04/15/2023
If the product is used in Japan and falls under the Cartagena Law, it needs to be controlled appropriately.
BRAF-550H 04/15/2023
This protein is not a living modified organism, so it does not apply to the Cartagena Law in Japan. No worries.
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