Recombinant Human CTHRC1 protein, His-tagged

• Cat.No.: CTHRC1-3570H
• Product Overview: Recombinant Human CTHRC1 protein(1-243 aa), fused to His tag, was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Form: The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 300mM imidazole.
• Protein length: 1-243 aa
• AA Sequence: MRPQGPAASPQRLRGLLLLLLLQLP APSSASEIPKGKQKAQLRQREVVDL YNGMCLQGPAGVPGRDGSPGANGIP GTPGIPGRDGFKGEKGECLRESFEE SWTPNYKQCSWSSLNYGIDLGKIAE CTFTKMRSNSALRVLFSGSLRLKCR NACCQRWYFTFNGAECSGPLPIEAI IYLDQGSPEMNSTINIHRTSSVEGL CEGIGAGLVDVAIWVGTCSDYPKGD ASTGWNSVSRIIIEELPK
• Purity: 90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
• Storage: Short-term storage: Store at 2-8°C for (1-2 weeks).
  Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.
• Reconstitution: Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage.
  Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage.

Gene Information

• Gene Name: CTHRC1 collagen triple helix repeat containing 1 [ Homo sapiens ]
• Official Symbol: CTHRC1
• Synonyms: CTHRC1; collagen triple helix repeat containing 1; collagen triple helix repeat-containing protein 1
• Gene ID: 115908
• mRNA Refseq: NM_001256099
• Protein Refseq: NP_001243028
• MIM: 610635
• UniProt ID: Q96CG8

Reviews

02/19/2023

Consistent quality, a go-to for researchers.

11/24/2018

Expertise and professionalism in every analysis.

06/22/2017

Reliable support for our protein studies.

Q&As

What factors regulate the expression and activity of CTHRC1 protein?

Environmental factors, inflammatory responses, and mechanical stress can regulate the expression and activity of CTHRC1.

What role does CTHRC1 protein play in tissue repair and remodeling?

CTHRC1 promotes cell migration and downregulates collagen synthesis in tissue repair, aiding in tissue remodeling.

How do structural changes in CTHRC1 protein affect its biological function?

Structural changes in CTHRC1 may affect its interactions with the extracellular matrix and other proteins, altering its function.

How does the interaction of CTHRC1 protein with the Wnt signaling pathway affect cell proliferation and differentiation?

The interaction of CTHRC1 with the Wnt signaling pathway influences cell proliferation and differentiation, especially in cancer and tissue repair.

What is the role of CTHRC1 protein in cardiovascular diseases?

In cardiovascular diseases, CTHRC1 is involved in the remodeling and repair of blood vessels.

How does CTHRC1 protein affect the invasiveness and metastasis of cancer cells?

CTHRC1 enhances cancer cell invasiveness and metastatic potential by facilitating extracellular matrix remodeling and signal transduction.

How does the expression level of CTHRC1 protein vary in different types of cancer?

CTHRC1 expression is often increased in various cancers, associated with aggressiveness and severity of the disease.