Recombinant Human EMG1 Nucleolar Protein Homolog(S. cerevisiae), His-tagged
Cat.No. : | EMG1-6938H |
Product Overview : | Recombinant human EMG1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. |
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Description : | EMG1 is a 244 amino acid protein that is thought to be involved in ribosome biogenesis. Localized to the nucleolus, EMG1 participates in pre-18S rRNA processing and may play an important role in the assembly of the small ribosomal subunit, possibly controlling methylation during ribosome synthesis. A mutation in this gene has been associated with Bowen-Conradi syndrome. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT. |
Molecular Mass : | 29.1 kDa (267aa), confirmed by MALDI-TOF |
Protein length : | 1-244aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMAAPSDG FKPRERSGGE QAQDWDALPP KRPRLGAGNK IGGRRLIVVL EGASLETVKV GKTYELLNCD KHKSILLKNG RDPGEARPDI THQSLLMLMD SPLNRAGLLQ VYIHTQKNVL IEVNPQTRIP RTFDRFCGLM VQLLHKLSVR AADGPQKLLK VIKNPVSDHF PVGCMKVGTS FSIPVVSDVR ELVPSSDPIV FVVGAFAHGK VSVEYTEKMV SISNYPLSAA LTCAKLTTAF EEVWGVI |
Purity : | >95% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name : | EMG1 EMG1 nucleolar protein homolog (S. cerevisiae) [ Homo sapiens ] |
Official Symbol : | EMG1 |
Synonyms : | EMG1; EMG1 nucleolar protein homolog (S. cerevisiae); ribosomal RNA small subunit methyltransferase NEP1; C2F; Grcc2f; NEP1; essential for mitotic growth 1; ribosome biogenesis protein NEP1; 18S rRNA Psi1248 methyltransferase; 18S rRNA (pseudouridine-N1-)-methyltransferase NEP1; FLJ60792; |
Gene ID : | 10436 |
mRNA Refseq : | NM_006331 |
Protein Refseq : | NP_006322 |
MIM : | 611531 |
UniProt ID : | Q92979 |
Chromosome Location : | 12p13 |
Pathway : | Ribosome biogenesis in eukaryotes, organism-specific biosystem; Ribosome biogenesis in eukaryotes, conserved biosystem; |
Function : | RNA binding; methyltransferase activity; rRNA (pseudouridine) methyltransferase activity; rRNA binding; transferase activity; |
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◆ Lysates | ||
EMG1-6611HCL | Recombinant Human EMG1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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