Recombinant Human Uroplakin 3A, His-tagged
Cat.No. : | UPK3A-4747H |
Product Overview : | Recombinant human UPK3A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. |
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Cat. No. : | UPK3A-4747H |
Description : | UPK3A belongs to the uroplakin-3 family. Uroplakins (UP) are key components of the urothelium. They are transmembrane proteins that pass the lipid bilayer once (UPII, UPIIIa, and UPIIIb) or four times (UPIa and UPIb; both belonging to the "tetraspanin" family). All have large luminal/extracellular domains, but only UPIIIa and UPIIIb have significant cytoplasmic portions in their C-termini. UPK3A is a highly specific and moderately sensitive immunohistochemical marker for primary and metastatic urothelial carcinomas. Mutations in this gene may be associated with renal adysplasia |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 150mM NaCl |
Molecular Weight : | 23.1kDa (214aa), confirmed by MALDI-TOF |
Purity : | > 90% by SDS - PAGE |
Concentration : | 0.25mg/ml (determined by Bradford assay) |
Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MGSHMVNLQP QLASVTFATN NPTLTTVALE KPLCMFDSKE ALTGTHEVYL YVLVDSAISR NASVQDSTNT PLGSTFLQTE GGRTGPYKAV AFDLIPCSDL PSLDAIGDVS KASQILNAYL VRVGANGTCL WDPNFQGLCN PPLSAATEYR FKYVLVNMST GLVEDQTLWS DPIRTNQLTP YSTIDTWPGR RSGG |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | UPK3A uroplakin 3A [ Homo sapiens ] |
Official Symbol : | UPK3A |
Synonyms : | UPK3A; UP3A; UPK3; UPIII; UPIIIA; MGC119178; uroplakin-3a; uroplakin III; OTTHUMP00000199859; OTTHUMP00000199860; uroplakin 3A; Uroplakin III; uroplakin 3; UP3a |
Gene ID : | 7380 |
mRNA Refseq : | NM_006953 |
Protein Refseq : | NP_008884 |
MIM : | 611559 |
UniProt ID : | O75631 |
Chromosome Location : | 22q13.31 |
Products Types
◆ Recombinant Protein | ||
Upk3a-285R | Recombinant Rat Upk3a Protein, His-tagged | +Inquiry |
UPK3A-2498M | Recombinant Mouse UPK3A Protein (19-207 aa), His-Myc-tagged | +Inquiry |
UPK3A-284H | Recombinant Human UPK3A Protein, His-tagged | +Inquiry |
UPK3A-9928M | Recombinant Mouse UPK3A Protein, His (Fc)-Avi-tagged | +Inquiry |
UPK3A-31078TH | Recombinant Human UPK3A, His-tagged | +Inquiry |
◆ Lysates | ||
UPK3A-724HCL | Recombinant Human UPK3A lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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