Recombinant Human Wolf-Hirschhorn Syndrome Candidate 2, T7-tagged
Cat.No. : |
WHSC2-3015H |
Product Overview : |
Recombinant Human WHSC2 protein was expressed in E.coli with T7-tag at the N-terminus. The molecular weight is 57349 Da(525 aa). |
- Specification
- Gene Information
- Related Products
Cat. No. : |
WHSC2-3015H |
Description : |
Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. WHSC2 encodes the NELF-A subunit of the NELF complex. |
Sequences of amino acids : |
1-525 aa |
Formulation : |
10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3. 10mM DTT. |
Purity : |
90% |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.