Recombinant Human XPO5 protein, Myc/DDK-tagged
Cat.No. : | XPO5-1405H |
Product Overview : | Purified recombinant protein of Homo sapiens exportin 5 (XPO5) with C-terminal MYC/DDK tag, was expressed in HEK293T cells. |
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Description : | This gene encodes a member of the karyopherin family that is required for the transport of small RNAs and double-stranded RNA-binding proteins from the nucleus to the cytoplasm. The encoded protein translocates cargo through the nuclear pore complex in a RanGTP-dependent process. |
Source : | HEK293T |
Species : | Human |
Tag : | Myc&DDK |
Molecular Mass : | 136.1 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Gene Name : | XPO5 exportin 5 [ Homo sapiens (human) ] |
Official Symbol : | XPO5 |
Synonyms : | XPO5; exportin 5; exp5; exportin-5; ran-binding protein 21 |
Gene ID : | 57510 |
mRNA Refseq : | NM_020750 |
Protein Refseq : | NP_065801 |
MIM : | 607845 |
UniProt ID : | Q9HAV4 |
Products Types
◆ Recombinant Protein | ||
XPO5-10236M | Recombinant Mouse XPO5 Protein, His (Fc)-Avi-tagged | +Inquiry |
XPO5-397H | Recombinant Human XPO5 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
XPO5-5044R | Recombinant Rhesus Macaque XPO5 Protein, His (Fc)-Avi-tagged | +Inquiry |
XPO5-2368H | Recombinant Human XPO5 Protein, His (Fc)-Avi-tagged | +Inquiry |
XPO5-18631M | Recombinant Mouse XPO5 Protein | +Inquiry |
◆ Lysates | ||
XPO5-1938HCL | Recombinant Human XPO5 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewThe XPO5 protein comes highly recommended for its excellent performance in various research applications.
Researchers can confidently rely on its capabilities to generate precise and significant results, enhancing the understanding of protein function and dynamics.
It has demonstrated exceptional effectiveness in WB experiments, showcasing its reliability and precision in detecting and quantifying specific targets.
Q&As (5)
Ask a questionTargeting XPO5 for cancer therapy involves the development of small molecule inhibitors that can disrupt its function, potentially leading to the suppression of tumor growth.
XPO5 protein plays a role in the export of specific microRNAs that can modulate immune responses, suggesting its involvement in immune-related diseases and therapies.
Research suggests that dysregulation of XPO5 protein expression may serve as a potential biomarker for certain diseases, including cancer and cardiovascular disorders.
Currently, there are ongoing clinical trials investigating the efficacy of XPO5 inhibitors in the treatment of certain types of cancer and other diseases.
XPO5 protein has been found to regulate the export of specific microRNAs that are involved in neuronal development and function, suggesting its potential involvement in neurological disorders.
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