Recombinant Mouse Gap43 Protein, Myc/DDK-tagged

• Cat.No.: Gap43-3149M
• Product Overview: Purified recombinant protein of mouse full-length growth associated protein 43 (Gap43), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 24.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Gap43 growth associated protein 43 [ Mus musculus (house mouse) ]
• Official Symbol: Gap43
• Synonyms: Gap43; growth associated protein 43; Ba; B-50; GAP-; Basp2; GAP-43; neuromodulin; axonal membrane protein GAP-43; brain abundant, membrane attached signal protein 2; calmodulin-binding protein P-57; growth accentuating protein 43
• Gene ID: 14432
• mRNA Refseq: NM_008083
• Protein Refseq: NP_032109
• UniProt ID: P06837

Reviews

05/14/2022

The protein composition was stable and concentrated, allowing me to obtain satisfactory experimental results.

03/12/2022

The technical expert will follow up on the progress of my experiments and provide constructive advice on the problems that arise in my experiments.

02/04/2022

The technician modified my experimental protocol so that my experiment went smoothly.

Q&As

What diseases is GAP43 closely associated with the study of?

GAP43 is closely related to the study of non-small cell lung cancer, thyroid cancer, astrocyte cancer and other diseases.

What biological processes is GAP43 involved in?

GAP43 is widely involved in neural development and regeneration, regulating neurotransmitter release, cytosis, synaptic vesicle recycling, etc.

What are the effects of upregulating GAP43 expression?

Up-regulation of GAP43 expression was able to inhibit the proliferation, migration and invasion of colorectal cancer cells to a great extent.

Where is GAP43 mainly expressed?

GAP43 is specifically expressed in neural tissues.

How is GAP43 related to DDX3X?

GAP43 interacts with DDX3X.