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ACTA2

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Official Full Name
actin, alpha 2, smooth muscle, aorta
Background
The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]
Synonyms
ACTA2; actin, alpha 2, smooth muscle, aorta; AAT6; ACTSA; MYMY5; actin, aortic smooth muscle; alpha-cardiac actin; cell growth-inhibiting gene 46 protein;
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ACTA2 Related Articles
>> Granata, A; Bernard, WG; et al. Temporal and Embryonic Lineage-Dependent Regulation of Human Vascular SMC Development by NOTCH3. STEM CELLS AND DEVELOPMENT 24:846-856(2015).
>> Kurahara, LH; Sumiyoshi, M; et al. Intestinal Myofibroblast TRPC6 Channel May Contribute to Stenotic Fibrosis in Crohn's Disease. INFLAMMATORY BOWEL DISEASES 21:496-506(2015).

45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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