APCS
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Official Full Name
amyloid P component, serum
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Overview
The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. -
Synonyms
APCS; amyloid P component, serum; SAP; PTX2; MGC88159; serum amyloid P-component; pentaxin-related; OTTHUMP00000024355; 9.5S alpha-1-glycoprotein;
- Recombinant Proteins
- Cell & Tissue Lysates
- Native Proteins
- Protein Pre-coupled Magnetic Beads
- Others
- Transfected Stable Cell Lines
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- Human Cell
- Human Serum
- Mammalian cells
- Mouse Serum
- Wheat Germ
- C
- His
- Myc
- DDK
- Flag
- GST
- His (Fc)
- Avi
- Myc|DDK
- N/A
- N
- T7
- Involved Pathway
- Protein Function
- Interacting Protein
- APCS Related Articles
APCS involved in several pathways and played different roles in them. We selected most pathways APCS participated on our site, such as Amyloid formation, Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with APCS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Amyloid formation | HIST2H3C;LTF;CST3;HIST3H2BB;HIST4H4;RHBDL1;NAT8B;TGFBI;CEACAM21 |
Metabolism of proteins | GALNT6;PPP6R3;B3GNT3;GRPEL2;TBCD;MUC4;SERP1;UBA2;CTSH |
APCS has several biochemical functions, for example, calcium ion binding, carbohydrate binding, complement component C1q binding. Some of the functions are cooperated with other proteins, some of the functions could acted by APCS itself. We selected most functions APCS had, and list some proteins which have the same functions with APCS. You can find most of the proteins on our site.
Function | Related Protein |
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calcium ion binding | FAT1A;NCALDA;GSNA;PCDH2AA3;PCDH1G31;RHOT1B;IHH;MYL2;THBS2 |
carbohydrate binding | CHI3L1;CHI3L2;POC1BL;ACAN;GALNTL6;CLEC7A;GFPT2;GALNT2;CLEC4F |
complement component C1q binding | CD93;C1QBP;C4A;PTX3;CALR;APCS;CRP |
unfolded protein binding | CLPX;HSPA8;APCS;CDC37L1;HSPA9;SSUH2.2;PFDN6;CLPXA;ST13 |
virion binding | PPIA;HSP90B1;CD209;PTX3;HIPK2;PVRL1;CLEC4M;TSG101;APCS |
APCS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APCS here. Most of them are supplied by our site. Hope this information will be useful for your research of APCS.
GOT2; GK; GRB2; HES1; COPS5; d-mannose
- Q&As
- Reviews
Q&As (20)
Ask a questionThe duration of use of therapy depends on the type of disease and treatment regimen, and needs to be carried out under the guidance of a professional physician.
The advantages and disadvantages of s versus other treatments need to be evaluated in the context of the specific disease and treatment regimen.
The specificity and specificity of s allow them to be used in precision medicine to achieve personalized treatment.
The stability of the is one of the important factors for its clinical application, and poor stability of the protein may lead to adverse reactions in patients or reduce the therapeutic effect.
Recombinant proteins, as exogenous proteins, may cause a response from the immune system, but there are already several techniques used to reduce their immunogenicity.
Recombinant proteins can be used in vaccine preparation, and there are already several vaccines based on s on the market.
The efficacy of s and traditional drugs depends on the type of disease and individual differences, and needs to be selected on a case-by-case basis.
Recombinant proteins can be used to treat a variety of diseases, such as immune deficiency diseases, tumors, cardiovascular diseases, etc.
Recombinant proteins usually need to be administered intravenously, but there are also some oral s that are currently being studied.
With the advancement of technology, the preparation of s has also been continuously improved, and large-scale production has become possible.
Any medical technology and drug treatment has a certain risk, is no exception, need to be reasonable application under the guidance of professional doctors.
The preparation of s is subject to compliance with relevant policies and regulations, particularly with regard to biosafety.
Recombinant protein therapy should follow the basic principles of individuality, pertinence, safety and effectiveness.
The pharmacokinetics and pharmacodynamics of s have been clearly understood, but they still need to be explored and perfected in clinical practice.
The production cost of is relatively high, but because of its therapeutic effect and broad application prospects, it has become an important field in the pharmaceutical industry.
The application of s needs to be adjusted individually according to the specific situation of the patient in order to achieve the optimal therapeutic effect.
Recombinant proteins have been used in the treatment of various neurological diseases, such as multiple sclerosis and Parkinson's disease.
As a new drug therapy technology, has broad application prospects, and more s may be used in the future.
Recombinant proteins are subject to various metabolic and decomposition influences in the body, and different proteins will have different stability and half-lives.
Clinical trials of s are subject to strict compliance with relevant ethical and regulatory requirements and are subject to regulatory approval and supervision.
Customer Reviews (4)
Write a reviewShort half-life and high clearance.
APCS produced by them has low preparation cost and high cost performance.
Stability of APCS is very good, and it can maintain stable performance even in extreme environments, which shows its excellent adaptability and reliability.
Production process is very much in line with the principle of green production.
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