| Description : |
Pentraxin2, also known as serum amyloid P-component, is a secreted serum glycoprotein that belongs to the pentraxins family. This family binds calcium-dependent lectin-like manner and is characterized distinctive flattened ß-jellyroll structure similar to the legume lectins. This protein is a non-fibrillar component, it can interact with DNA and histones. It regulates the solubility of amyloid fibrils and protects them from degradation by proteolytic enzymes and phagocytic cells. This protein is the major acute-phase protein and expression of it is dependent on complement activation, IL-6 and/or IL-1 beta. Recombinant mouse Pentraxin2 protein, fused to His-tag at C-terminus, was expressed in HEK293 and purified by using conventional chromatography techniques. |
| Source : |
HEK293 |
| Species : |
Mouse |
| Tag : |
His |
| Form : |
Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10 % glycerol. |
| Molecular Mass : |
24.6 kDa |
| Protein length : |
21-224 aa |
| AA Sequence : |
QTDLKRKVFV FPRESETDHV KLIPHLEKPL QNFTLCFRTY SDLSRSQSLF SYSVKGRDNE LLIYKEKVGE YSLYIGQSKV TVRGMEEYLS PVHLCTTWES SSGIVEFWVN GKPWVKKSLQ REYTVKAPPS IVLGQEQDNY GGGFQRSQSF VGEFSDLYMW DYVLTPQDIL FVYRDSPVNP NILNWQALNY EINGYVVIRP RVWDHHHHHH |
| Endotoxin : |
< 1.0 EU per 1 ug of protein (determined by LAL method) |
| Purity : |
> 90 % by SDS - PAGE |
| Notes : |
For research use only. This product is not intended or approved for human, diagnostics or veterinary use. |
| Storage : |
Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 or -70 centigrade. Avoid repeated freezing and thawing cycles. |
| Concentration : |
0.25 mg/ml (determined by Absorbance at 280 nm) |
