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Official Full Name
brain-derived neurotrophic factor
The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimers and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Jan 2009]
BDNF; brain-derived neurotrophic factor; ANON2; BULN2; abrineurin; neurotrophin;
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BDNF Related Articles
>> Nam, JH; Leem, E; et al. Induction of GDNF and BDNF by hRheb(S16H) Transduction of SNpc Neurons: Neuroprotective Mechanisms of hRheb(S16H) in a Model of Parkinson's Disease. MOLECULAR NEUROBIOLOGY 51:487-499(2015).
>> Jeon, MT; Nam, JH; et al. In Vivo AAV1 Transduction With hRheb(S16H) Protects Hippocampal Neurons by BDNF Production. MOLECULAR THERAPY 23:445-455(2015).

BDNF Related Gene Family

45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127

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