casp3
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  • Official Full Name
  • caspase 3, apoptosis-related cysteine peptidase
  • Background
  • This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
  • Synonyms
  • CASP3; caspase 3, apoptosis-related cysteine peptidase; CPP32; SCA-1; CPP32B; Apopain; CPP-32; EC 3.4.22.56; Yama; procaspase3; Cysteine protease CPP32; PARP cleavage protease; SREBP cleavage activity 1; Yama protein; caspase 3, apoptosis-related cysteine protease
Cat.#:CASP3-0421HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CASP3 Protein, GST-Tagged
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Cat.#:CASP3-1642HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Caspase 3, Apoptosis-related Cysteine Peptidase
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Cat.#:Casp3-1641MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Caspase 3
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Cat.#:Casp3-1644RTag:N/A
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Caspase 3
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Cat.#:CASP3-158HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CASP3
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Cat.#:CASP3-192HTag:Met&His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CASP3, Met&His-tagged
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Cat.#:CASP3-26768THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CASP3
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Cat.#:CASP3-293HTag:His/MBP
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CASP3 protein, His/MBP-tagged
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Cat.#:CASP3-334HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CASP3 protein, GST-tagged
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Cat.#:CASP3-342HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CASP3, His tagged
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Cat.#:CASP3-483HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human CASP3
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Cat.#:CASP3-621HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CASP3 protein, His-tagged
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Cat.#:CASP3-622HTag:His & T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CASP3 protein, His & T7-tagged
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Cat.#:Casp3-1643MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Casp3 protein
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Cat.#:CASP3-2752MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CASP3 Protein
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Cat.#:Casp3-623MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Casp3 protein, His-tagged
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Cat.#:CASP3-1145RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CASP3 Protein
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Cat.#:Casp3-624RTag:His & T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Casp3 protein, His & T7-tagged
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Cat.#:Casp3-625RTag:His & T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Casp3 protein, His & T7-tagged
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Cat.#:CASP3-362CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CASP3 Protein, His-tagged
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Cat.#:CASP3-6290CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CASP3
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Cat.#:CASP3-36HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CASP3, His-tagged
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Cat.#:Casp3-748RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Caspase 3, His-tagged
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Cat.#:CASP3-7838HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CASP3 293 Cell Lysate
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Cat.#:CASP3-7839HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CASP3 293 Cell Lysate
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Cat.#:CBCRY39Tag:
Source (Host):E. coliSpecies:
Product nameCaspase-3
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Casp3 Related Articles

Accialini, P; Hernandez, SF; et al. A link between Notch and progesterone maintains the functionality of the rat corpus luteum. REPRODUCTION 149:1-10(2015).
Chen, TC; Lin, KT; et al. Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein-Protein Interactions in a Pathway Network. JOURNAL OF PROTEOME RESEARCH 13:5339-5346(2014).