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CD14

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Official Full Name
CD14 molecule
Background
The protein encoded by this gene is a component of the innate immune system. CD14 exists in two forms. Either it is anchored into the membrane by a glycosylphosphatidylinositol tail (mCD14) or it appears in a soluble form (sCD14). Soluble CD14 either appears after shedding of mCD14 (48 KDa) or is directly secreted from intracellular vesicles (56 KDa). CD14 takes its name from its inclusion in the cluster of differentiation group of cell surface marker proteins. CD14 was the first described pattern recognition receptor.
Synonyms
CD14; monocyte differentiation antigen CD14; OTTHUMP00000159892; OTTHUMP00000223710; OTTHUMP00000223711; OTTHUMP00000224328; myeloid cell-specific leucine-rich glycoprotein
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Cd14 Related Articles
>> Dickson, MC; Ludbrook, VJ; et al. A model of skin inflammation in humans leads to a rapid and reproducible increase in the interferon response signature: a potential translational model for drug development. INFLAMMATION RESEARCH 64:171-183(2015).
>> Troseid, M; Nestvold, TK; et al. Soluble CD14 Is Associated with Markers of Vascular Dysfunction in Bariatric Surgery Patients. METABOLIC SYNDROME AND RELATED DISORDERS 13:119-124(2015).

45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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