cd74
Share
  • Official Full Name
  • CD74 molecule, major histocompatibility complex, class II invariant chain
  • Background
  • The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
  • Synonyms
  • CD74; CD74 molecule, major histocompatibility complex, class II invariant chain; II; DHLAG; HLADG; Ia-GAMMA; HLA class II histocompatibility antigen gamma chain; p33; HLA-DR-gamma; MHC HLA-DR gamma chain; Ia-associated invariant chain; gamma chain of class II antigens; HLA-DR antigens-associated invariant chain; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated);
Cat.#:CD74-114HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human CD74, His-tagged
+Inquiry
Cat.#:CD74-2227HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD74, His tagged
+Inquiry
Cat.#:CD74-2228HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD74, Myc-DDK-Tagged
+Inquiry
Cat.#:CD74-2229HTag:N/A
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human CD74
+Inquiry
Cat.#:CD74-2230HTag:GST
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human CD74, GST-Tagged
+Inquiry
Cat.#:CD74-2231HTag:Hemagglutinin
Source (Host):CHOSpecies:Human
Product nameRecombinant Human CD74, Hemagglutinin-tagged
+Inquiry
Cat.#:CD74-2232HTag:HA
Source (Host):CHOSpecies:Human
Product nameRecombinant Human CD74, HA-tagged
+Inquiry
Cat.#:CD74-546HTag:HA
Source (Host):CHO CellsSpecies:Human
Product nameRecombinant Human CD74 Protein, HA-tagged
+Inquiry
Cat.#:Cd74-641MTag:HA
Source (Host):CHO CellsSpecies:Mouse
Product nameRecombinant Mouse Cd74 Protein, HA-tagged
+Inquiry
Cat.#:CD74-9493MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CD74, His-tagged
+Inquiry
Cat.#:CD74-1262RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CD74 Protein
+Inquiry
Cat.#:CD74-1132CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CD74
+Inquiry
Cat.#:CD74-2603HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD74 cell lysate
+Inquiry

CD74 Related Articles

Zou, HLY; Li, QH; et al. PF-06463922 is a potent and selective next-generation ROS1/ALK inhibitor capable of blocking crizotinib-resistant ROS1 mutations. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:3493-3498(2015).
Setti, SE; Littlefield, AM; et al. Diet-induced obesity attenuates endotoxin-induced cognitive deficits. PHYSIOLOGY & BEHAVIOR 141:1-8(2015).