Recombinant Mouse Cd74 Protein, MYC/DDK-tagged

• Cat.No.: Cd74-1231M
• Product Overview: Purified recombinant protein of full-length mouse CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) (Cd74), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Description: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.
• Source: HEK293T
• Species: Mouse
• Tag: MYC/DDK
• Molecular Mass: 24.9 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) [ Mus musculus (house mouse) ]
• Official Symbol: Cd74
• Synonyms: Cd74; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); Ii; CLIP; DHLAG; HLADG; Ia-GAMMA; H-2 class II histocompatibility antigen gamma chain; HLA-DR-GAMMA; Ia-associated invariant chain; MHC class II-associated invariant chain; class II-associated invariant chain peptide; dinucleotide microsatellite; histocompatibility: class II antigens, gamma chain of; ia antigen-associated invariant chain; invariant polypeptide of major histocompatibility complex, class II antigen-associated
• Gene ID: 16149
• mRNA Refseq: NM_010545
• Protein Refseq: NP_034675
• UniProt ID: Q545Y5