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CTGF
Official Full Name
connective tissue growth factor
Background
The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis.
Synonyms
CTGF; connective tissue growth factor; CCN2; IGFBP8; CCN 2; CCN family member 2; CTGF_HUMAN; Hcs 24; Hcs24; Hypertrophic chondrocyte specific protein 24; Hypertrophic chondrocyte-specific gene product 24; Hypertrophic chondrocyte-specific protein 24; IBP-8; IGF-binding protein 8; IGFBP-8; Insulin like Growth Factor Binding Protein 8; Insulin-like Growth Factor-Binding Protein 8; MGC102839; NOV 2; NOV2