Recombinant Human CTGF protein, His-tagged

• Cat.No.: CTGF-2466H
• Product Overview: Recombinant Human CTGF protein(297-349 aa), fused to His tag, was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Form: The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 300mM imidazole.
• Protein length: 297-349 aa
• AA Sequence: RTTTLPVEFKCPDGEVMKKNMMFIK TCACHYNCPGDNDIFESLYYRKMYG DMA
• Purity: 95%, by SDS-PAGE with Coomassie Brilliant Blue staining.
• Storage: Short-term storage: Store at 2-8°C for (1-2 weeks).
  Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.
• Reconstitution: Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage.
  Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage.

Gene Information

• Gene Name: CTGF connective tissue growth factor [ Homo sapiens ]
• Official Symbol: CTGF
• Synonyms: CTGF; connective tissue growth factor; CCN2; IGFBP8; IBP-8; IGFBP-8; CCN family member 2; IGF-binding protein 8; hypertrophic chondrocyte-specific protein 24; insulin-like growth factor-binding protein 8; NOV2; HCS24; MGC102839
• Gene ID: 1490
• mRNA Refseq: NM_001901
• Protein Refseq: NP_001892
• MIM: 121009
• UniProt ID: P29279

Reviews

03/22/2021

Its purity, stability, and consistency ensure reliable and reproducible results, giving me confidence in the integrity of my research findings.

08/06/2019

With their assistance, I can overcome obstacles and optimize my experimental setup.

09/23/2018

With the CTGF protein and the manufacturer's support, I am confident in obtaining accurate and meaningful results for my scientific investigations.

Q&As

How can CTGF be measured or detected in clinical settings?

CTGF levels can be measured using various techniques, including enzyme-linked immunosorbent assay (ELISA) and immunohistochemistry.

What are the potential diagnostic applications of CTGF in medicine?

CTGF levels can serve as diagnostic markers for fibrotic diseases, aiding in the early detection and monitoring of such conditions.

Are there therapeutic implications of targeting CTGF in clinical practice?

Yes, targeting CTGF is being explored as a potential therapeutic strategy to mitigate fibrosis in various organs and tissues.

In which medical specialties is CTGF protein research particularly relevant?

CTGF protein research is particularly relevant in specialties such as rheumatology, pulmonology, and dermatology due to its implications in fibrotic diseases.

How does CTGF contribute to fibrosis?

CTGF plays a crucial role in promoting the formation of fibrous tissue by stimulating the production of extracellular matrix proteins.