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Official Full Name
cysteine-rich, angiogenic inducer, 61
The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apoptosis, and extracellular matrix formation. [provided by RefSeq, Sep 2011]
CYR61; cysteine-rich, angiogenic inducer, 61; CCN1; GIG1; IGFBP10; protein CYR61; IBP-10; IGFBP-10; CCN family member 1; IGF-binding protein 10; cysteine-rich, anigogenic inducer, 61; cysteine-rich heparin-binding protein 61; insulin-like growth factor-binding protein 10;
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CYR61 Related Articles
>> Park, YS; Hwang, S; et al. CCN1 Secreted by Tonsil-Derived Mesenchymal Stem Cells Promotes Endothelial Cell Angiogenesis via Integrin alpha(v)beta(3) and AMPK. JOURNAL OF CELLULAR PHYSIOLOGY 230:140-149(2015).
>> Chen, CY; Su, CM; et al. CCN1 Induces Oncostatin M Production in Osteoblasts via Integrin-Dependent Signal Pathways. PLOS ONE 9:-(2014).

45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127

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