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DHH

  • Official Full Name

    desert hedgehog

  • Overview

    This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-
  • Synonyms

    DHH; desert hedgehog; desert hedgehog protein; Desert hedgehog (Drosophila) homolog; Desert hedgehog homolog (Drosophila); Desert hedgehog protein precursor; HHG-3; C78960;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • Met
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DHH-967H Active Recombinant Human DHH E.coli Met Cys23-Gly198 (Cys23Ile-Ile)
Human DHH-267H Recombinant Human desert hedgehog, His-tagged E.coli His
Human DHH-2589H Recombinant Human DHH Protein, GST-tagged Wheat Germ GST
Human DHH-345H Recombinant Human DHH protein E.coli N/A 177
Human DHH-11968H Recombinant Human DHH, His-tagged E.coli His C-term-346a.a.
Human DHH-469HCL Recombinant Human DHH cell lysate N/A
Human DHH-1337H Recombinant Human DHH Protein, His-tagged E.coli N-His Cys199-Gly396
Human DHH-2122H Recombinant Human DHH Protein (Leu241-Tyr383), N-His tagged E.coli N-His Leu241-Tyr383
Human DHH-2531HF Recombinant Full Length Human DHH Protein, GST-tagged In Vitro Cell Free System GST 396 amino acids
Human DHH-432D Active Recombinant Human DHH Protein (177 aa) E.coli 177
Mouse Dhh-384M Active Recombinant Mouse Dhh protein E.coli N/A 176 amino acids
Mouse Dhh-393M Recombinant Mouse Dhh protein E.coli N/A 177
Mouse Dhh-7883M Recombinant Mouse Dhh protein, His-tagged E.coli His Glu212~Glu392 (Accession # Q61488)
Mouse Dhh-431D Active Recombinant Mouse Dhh Protein (176 aa) E.coli 176
Zebrafish DHH-3242Z Recombinant Zebrafish DHH Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DHH Related Articles
  • DHH Related Research Area

DHH involved in several pathways and played different roles in them. We selected most pathways DHH participated on our site, such as Hedgehog signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DHH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Hedgehog signaling pathwayWNT1;PRKACAA;PRKACB;ZIC2B;LRP2A;WNT11;IHH;DYRK1AA;BMP2

DHH has several biochemical functions, for example, calcium ion binding, patched binding, peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DHH itself. We selected most functions DHH had, and list some proteins which have the same functions with DHH. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingPCDHB6;MMP28;DGKAA;DLL4;ATP2A2;EFCAB4A;EHD1B;SGCA;CASQ2
patched bindingCAV1;IHH;DHH;BBS1;SMO;CCNB1;SETD6;Shh;PTCH1
peptidase activityKLK7;CASP3A;ELA3L;FAM49BA;PGCP;MCPT2;AGA;CTSLA;BMP1B
protein bindingCDKN1B;CSE1L;XK;SETDB1;CPSF6;SGK1;RBM14;ELMO1;SSTR2
zinc ion bindingNEURL3;TRIM64C;AKAP8;UQCRC2A;S100A13;CD4;RNF39;TRIM35-35;ZDHHC21

DHH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DHH here. Most of them are supplied by our site. Hope this information will be useful for your research of DHH.

Nichols, P; Li, L; et al. Rational design of viscosity reducing mutants of a monoclonal antibody: Hydrophobic versus electrostatic inter-molecular interactions. MABS 7:212-230(2015).
Remedio, L; Carvalho, T; et al. Context- and Cell-Dependent Effects of Delta-Like 4 Targeting in the Bone Marrow Microenvironment. PLOS ONE 7:-(2012).
  • Q&As
  • Reviews

Q&As (6)

Ask a question
Does DHH protein deficiency affect reproductive development? 09/30/2022

There is no conclusive evidence that DHH protein deficiency affects the development of the reproductive system, but research suggests that it may be involved in the development of the male reproductive system.

What is the function of DHH protein in the cardiovascular system? 04/27/2022

The function of DHH protein in the cardiovascular system is unknown, but studies suggest that it may be involved in the differentiation and maturation process of cardiomyocytes.

How is DHH protein related to autism? 02/13/2022

Studies have shown that DHH protein may be involved in the development of autism, but the specific mechanism is not clear.

What is the function of DHH protein in the nervous system? 01/31/2021

The function of DHH protein in the nervous system is mainly to promote the differentiation and maturation of neurons, as well as the formation of synapses and the conduction of nerve signals.

Does DHH protein deficiency affect mental development? 09/28/2020

DHH protein deficiency may affect mental development, but the exact extent of the effect needs further research.

How is DHH protein related to arthritis? 06/17/2020

Studies have shown that DHH protein may play an important role in the pathogenesis of arthritis, but its specific role needs to be further studied.

Customer Reviews (3)

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Reviews
08/26/2022

    DHH has good stability under different environmental conditions

    07/18/2021

      DHH plays a significant role in signal transduction pathways.

      04/28/2021

        DHH has good absorbability and high bioavailability.

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