f8
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  • Official Full Name
  • coagulation factor VIII, procoagulant component
  • Background
  • Factor VIII (FVIII) is an essential blood-clotting protein, also known as anti-hemophilic factor (AHF). In humans, factor VIII is encoded by the F8 gene. Defects in this gene results in hemophilia A, a recessive X-linked coagulation disorder. Factor VIII is produced in liver sinusoidal cells and endothelial cells outside of the liver throughout the body. This protein circulates in the bloodstream in an inactive form, bound to another molecule called von Willebrand factor, until an injury that damages blood vessels occurs. In response to injury, coagulation factor VIII is activated and separates from von Willebrand factor. The active protein (sometimes written as coagulation factor VIIIa) interacts with another coagulation factor called factor IX. This interaction sets off a chain of additional chemical reactions that form a blood clot.
  • Synonyms
  • Factor VIII; FVIII; F8; coagulation factor VIII, procoagulant component; AHF; F8B; F8C; HEMA; FVIII; DXS1253E; coagulation factor VIII; factor VIII F8B; antihemophilic factor; coagulation factor VIIIc
Cat.#:F8-2397HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Coagulation Factor VIII, Procoagulant Component
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Cat.#:F8-3065HTag:N/A
Source (Host):Human plasmaSpecies:Human
Product nameHuman Factor-VIII
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Cat.#:F8-048HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human F8 Protein, His-tagged
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Cat.#:F8-12626HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human F8, His-tagged
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Cat.#:F8-125HTag:N/A
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Coagulation Factor VIII, Procoagulant Component
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Cat.#:F8-126HTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human F8, GST-tagged
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Cat.#:F8-6482HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human F8 293 Cell Lysate
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Cat.#:F8-25HTag:
Source (Host):Species:Human
Product nameHuman Blood Coagulation Factor VIII Reference standard
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Cat.#:F8-38HTag:
Source (Host):Species:Human
Product nameHuman Factor VIII Reference standard
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Cat.#:F8-P037HTag:
Source (Host):CHOSpecies:Human
Product nameRecombinant Human F8 therapeutic protein
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Cat.#:CSC-TP021Tag:
Source (Host):CHOSpecies:Human
Product nameHuman F8 Stable Cell Line-CHO
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F8 Related Articles

Anderson, DR; Cameron, AC; et al. WASP-20b and WASP-28b: a hot Saturn and a hot Jupiter in near-aligned orbits around solar-type stars. ASTRONOMY & ASTROPHYSICS 575:-(2015).
Hashemi, SM; Fischer, K; et al. Improved prediction of inhibitor development in previously untreated patients with severe haemophilia A. HAEMOPHILIA 21:227-233(2015).

F8 Related Gene Family

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