PML
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Official Full Name
PML promyelocytic leukemia
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Synonyms
PML; promyelocytic leukemia; protein PML; MYL; RNF71; TRIM19; RING finger protein 71; promyelocytic leukemia protein; tripartite motif protein TRIM19; probable transcription factor PML; promyelocytic leukemia, inducer of; tripartite motif-containing protein 19; PP8675;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rhesus Macaque
- E.coli
- HEK293
- HEK293T
- Insect Cell
- Mamanlian cells
- Mammalian Cell
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- PML Related Articles
PML involved in several pathways and played different roles in them. We selected most pathways PML participated on our site, such as Ubiquitin mediated proteolysis, Endocytosis, Influenza A, which may be useful for your reference. Also, other proteins which involved in the same pathway with PML were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ubiquitin mediated proteolysis | BTRC;UBE2U;UBOX5;HERC3;BRCA1;CUL1A;RCHY1;PML;ANAPC11 |
| Endocytosis | DNM2A;ARFGAP1;GBF1;ARFGEF1;WASH1;ARPC1B;PARD6GA;WASLB;CSF1R |
| Influenza A | NLRX1;TNFRSF10C;PRSS2;IFN-a;IFNA6;IFNG;PIK3R1;HSPA6;AGFG1 |
| Herpes simplex infection | TAF3;MAPK8;HLA-G;MAPK9;EEF1DB;PPP1CAA;PILRA;IFNA2;ARNTL |
| Pathways in cancer | LAMA4;PTGER3;FH;LAMB4;PML;FZD7;GNB1;CYCS;GNB4 |
| Transcriptional misregulation in cancer | RXRA;JMJD1C;IL2RB;PFTK1;SIX1;NFKB1;HOXA11;ATM;SFPI1 |
| Acute myeloid leukemia | RUNX1;RAF1;EIF4EBP1;TCF7L2;CCND1;MAP2K2;MAPK3;MAPK1;PIM2 |
PML has several biochemical functions, for example, DNA binding, SMAD binding, SUMO binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PML itself. We selected most functions PML had, and list some proteins which have the same functions with PML. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | PPARG;OLIG1;NR2F6B;EP300;SP2;KIN;HOXD3;ZFAND6;AKNA |
| SMAD binding | BMPR1A;HIPK2;MAGI2;COL3A1;AXIN1;TGFBR2;STUB1;EID2;FOXH1 |
| SUMO binding | USP25;HERC2;TOLLIP;RPS3;USPL1;PML;CBX4;TDG |
| cobalt ion binding | NUDT16;SLC11A2;BIRC5;PML;P2RX2 |
| protein binding | STXBP3;KLF4;FGFR1B;LYVE1;SLC16A3;RPA2;CHRAC1;TMEM19;EWSR1 |
| protein heterodimerization activity | JDP2;PRPH;TAS1R2;SCGB2A1;ATF1;HIST1H2BP;CEBPE;AOC3;H2-AA |
| protein homodimerization activity | VPS24;EPHX2;TSG101;NR2C1;DMRTB1;ABAT;CCBL1;ASNSD1;GPD1C |
| transcription coactivator activity | USP16;MYOD1;NCOA4;LPIN3;CTBP2;KAT6A;SUPT3H;VGLL2;ZEB1 |
| ubiquitin protein ligase binding | XBP1;TRAF1;TNFRSF1B;GLMN;UBE2J2;VCP;BLZF1;TP53;IKBKG |
| zinc ion binding | DTX2;SLC30A8;ARIH1;MLLT6;MMP20;ISL1L;PDLIM5;RNF138;ZFP37 |
PML has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PML here. Most of them are supplied by our site. Hope this information will be useful for your research of PML.
DAXX; KLHL20; TP53; SUMO1
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